Hydrogels for medical and related applications : a symposium (original) (raw)

A Comprehensive Review on Hydrogels

International Journal of Current Pharmaceutical Research, 2016

Polymers play a vital role in pharmaceutical development. Efforts have been continuously made to search a polymer that act in a controlled& desired way. Hydrogel development has solved many such issues. Hydrogels are hydrophilic, three-dimensional networks. Which are able to imbibe large amounts of water or biological fluids & thus resembles to a large extent, a biological tissue. They are insoluble due to the presence of physical or chemical crosslinks such as entanglements& crystallites. These materials can be synthesized to respond to a number of physiological stimuli present in the body, such as PH, ionic strength, temperature. The main aim of this article is to give a concise review on introduction, preparation methods, types, & various applications of hydrogels in the pharmaceutical field. Keywords: Hydrogels, Types of hydrogels, Preparation methods, Applications.

Hydrogels for Pharmaceutical and Biomedical Applications

Critical Reviews in Therapeutic Drug Carrier Systems, 2005

Hydrogels are crosslinked hydrophilic polymer structures that can imbibe large amounts of water or biological fl uids. Hydrogels are one of the upcoming classes of polymer-based systems that embrace numerous biomedical and pharmaceutical applications. Th is review discusses various parameters of hydrogels such as surface properties, water content and swelling behavior, eff ect of nature of polymer, ionic content, and thermodynamics, all of which can infl uence the biomedical usage of hydrogels. Meanwhile, intelligent or environment-sensitive hydrogels and bioadhesive hydrogels continue to be important materials for medical applications; therefore, a part of this review is devoted to some of their important classes. Hydrogels are extensively used for various biomedical applications-tissue engineering, molecular imprinting, wound dressings materials, immunoisolation, drug delivery, etc. Th us, this review aims to throw light on immense AU: "THE NUMEROUS"? applications that hydrogels have in the biomedical arena.

HYDROGEL IN PHARMACEUTICALS: A REVIEW

Hydrogel products constitute a group of polymeric materials, the hydrophilic structure of which renders them capable of holding large amounts of water in their three-dimensional networks. Extensive employment of these products in a number of industrial and environmental areas of application is considered to be of prime importance. As expected, natural hydrogels were gradually replaced by synthetic types due to their higher water absorption capacity, long service life, and wide varieties of raw chemical resources. Literature on this subject was found to be expanding, especially in the scientific areas of research. However, a number of publications and technical reports dealing with hydrogel products from the engineering points of view were examined to overview technological aspects covering this growing multidisciplinary field of research. The primary objective of this article is to review the literature concerning classification of hydrogels on different bases, its merits and demerits. It also involved technologies adopted for hydrogel production and its application in drug delivery.

Potential Applicabilities of Hydrogels - A Literature Survey

2012

Hydrogels are cross linked polymeric network, which have the ability to hold water within the space available among the polymeric chains. The hydrogels have been used extensively in various biomedical application, viz. drug delivery, cell carriers and/or entrapment, wound management and tissue engineering. Hydrogels are swellable polymeric materials, have been widely as a carrier of drug delivery systems. These biomaterials have gained attention owing to their peculiar characteristics like swelling in aqueous medium, pH and temperature sensitivity or sensitivity towards other stimuli. Hydrogels being biocompatible material have been recognized to function as drug protectors, especially of peptide and proteins, from in vivo environment. Also these swollen polymers are helpful as targetable carriers for bioactive drugs with tissue specificity and environmental sensitive hydrogels have enormous potential for various environmental variables, such as low pH and elevated temperature, are ...

Hydrogels for biomedical applications

Advanced Drug Delivery Reviews, 2002

This article reviews the composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices. The most important properties of hydrogels relevant to their biomedical applications are also identified, especially for use of hydrogels as drug and cell carriers, and as tissue engineering matrices.

Hydrogels: Properties and Applications in Biomedicine

Molecules

Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures, which can absorb relatively large amounts of fluid. Because of the high water content, soft structure, and porosity of hydrogels, they closely resemble living tissues. Research in recent years shows that hydrogels have been applied in various fields, such as agriculture, biomaterials, the food industry, drug delivery, tissue engineering, and regenerative medicine. Along with the underlying technology improvements of hydrogel development, hydrogels can be expected to be applied in more fields. Although not all hydrogels have good biodegradability and biocompatibility, such as synthetic hydrogels (polyvinyl alcohol, polyacrylamide, polyethylene glycol hydrogels, etc.), their biodegradability and biocompatibility can be adjusted by modification of their functional group or incorporation of natural polymers. Hence, scientists are still interested in the biomedical applications of hydrogels due to th...