5.47 Attentional Measures in Children and Adolescents With Bipolar Disorder (original) (raw)
2017, Journal of the American Academy of Child & Adolescent Psychiatry
Results: There was more illness and assortative mating for a mood disorder in both the patient's spouse (31 vs. 9%) and the patient's parents (21 vs. 3%) from the United States compared with Europe. In the parents of the US patients, assortative mating for a mood disorder was associated with more depression, bipolar disorder, alcohol, and other illnesses in the patient's offspring. Conclusions: This two-generation increase in assortative mating in the United States adds to the genetic vulnerability to mental illness in the offspring, further increasing the combined effects of greater amounts of psychosocial stress in the United States. The increases in childhood-onset illness driven by these factors deserve new efforts in research, clinical, and public health attempts to address and ameliorate this most unfortunate situation.
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