Evaluating Nerve Repair Outcomes in Complex Soft Tissue Reconstructions, a Multicenter Study Approach (original) (raw)

Abstract

Introduction: Severe trauma often results in complex peripheral nerve injuries that challenge even the most skilled reconstructive surgeon. As these injuries are highly variable, prospective clinical research on treatment algorithms are limited. In 2008, a multicenter, retrospective study was initiated to capture data on outcomes from the utilization of processed nerve allografts in today’s clinical practice. Analysis yielded a subgroup presenting with complex traumatic injuries requiring extensive soft tissue reconstructions. Here we report our findings on the outcomes of complex peripheral nerve injuries reconstructed using processed nerves allografts. Methods: The IRB approved study enrolled 12 sites with 25 contributing surgeons. Standardized data collection forms were completed for 132 individual nerve injuries. The aggregate data was reviewed to identify the subset of patients with multi-tissue, high energy, and extensive reconstructions. Quantitative assessment included: MRCC...

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