Cardiovascular damage in seronegative spondylarthritis (original) (raw)

One Health & Risk Management

Introduction. Cardiovascular mortality in patients diagnosed with seronegative spondyloarthritis (SSN) is on the rise. Impairment of the cardiovascular system in ankylosing spondylitis (SpA) is 20-40%, in psoriatic arthritis (APs) 18-22% and in reactive arthritis (ARe) 1-3%.Material and methods. The study included 77 patients diagnosed with SSN. Laboratory (erythrocyte sedimentation rate – ESR, C-reactive protein – CRP, fibrinogen) and instrumental (echocardiography – EcoCG, electrocardiogram – ECG) data were analyzed.Results. In 35 patients diagnosed with SpA, the left branch hemiblock of the Hiss bundle was determined – 71% and bradycardia – 57%. Aortic valve (VAo) changes were diagnosed in 54% and left ventricular hypertrophy (LVH) in 57%. Elevated CRP values were found in 34.5% of cases, ESR – 22.8% and fibrinogen – 17.2%. In 24 patients with APs, 33.5% showed VAo induration and fibrosis. Another change diagnosed in these patients was LVH (37.5%). Cardiac conductivity disorders ...

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