Triterpene saponins from the aerial parts of Dianthus caryophyllus var. remontant Hort (original) (raw)

Triterpenoid Saponins from the Roots of Gypsophila paniculata

Chinese Journal of Natural Medicines, 2010

Eleven triterpenoid saponins were isolated from the roots of Gypsophila trichotoma Wender. (G. trichotoma Wender. var. trichotoma) (Caryophyllaceae), together with one known compound. The structures were established on the basis of extensive NMR analysis (1 H, 13 C NMR, COSY, TOCSY, ROESY, HSQC, and HMBC), completed by analysis of HR-ESI-MS and ESI-MS n. The saponins have the commonly found gypsogenin as the aglycone substituted at C-3 with trisaccharide and at C-28 with oligosaccharide through a fucose residue, as saponins isolated from Gypsophila perfoliata L. originated from China. The oligosaccharide attached to C-28 is substituted with acetyl and (or) sulfate groups. The cytotoxicity of the saponin extract from G. trichotoma was evaluated against a rat alveolar macrophage-like cell line NR8383 and human leukemia cell lines U937 and BV-173. The synergistic effect of the aminoacyl saponins, previously isolated from G. trichotoma, was tested for its ability to enhance the cytotoxicity of the targeted toxin in HER14 cells.

Triterpenoid saponins from the roots of Gypsophila trichotoma Wender

Phytochemistry, 2013

Eleven triterpenoid saponins were isolated from the roots of Gypsophila trichotoma Wender. (G. trichotoma Wender. var. trichotoma) (Caryophyllaceae), together with one known compound. The structures were established on the basis of extensive NMR analysis ( 1 H, 13 C NMR, COSY, TOCSY, ROESY, HSQC, and HMBC), completed by analysis of HR-ESI-MS and ESI-MS n . The saponins have the commonly found gypsogenin as the aglycone substituted at C-3 with trisaccharide and at C-28 with oligosaccharide through a fucose residue, as saponins isolated from Gypsophila perfoliata L. originated from China. The oligosaccharide attached to C-28 is substituted with acetyl and (or) sulfate groups.

Acylated triterpenoid saponins from roots of Gypsophila trichotoma

Planta Medica, 2012

Eleven triterpenoid saponins were isolated from the roots of Gypsophila trichotoma Wender. (G. trichotoma Wender. var. trichotoma) (Caryophyllaceae), together with one known compound. The structures were established on the basis of extensive NMR analysis ( 1 H, 13 C NMR, COSY, TOCSY, ROESY, HSQC, and HMBC), completed by analysis of HR-ESI-MS and ESI-MS n . The saponins have the commonly found gypsogenin as the aglycone substituted at C-3 with trisaccharide and at C-28 with oligosaccharide through a fucose residue, as saponins isolated from Gypsophila perfoliata L. originated from China. The oligosaccharide attached to C-28 is substituted with acetyl and (or) sulfate groups.

Triterpenoid Glycosides from Leaves of Medicago arborea L

Journal of Agricultural and Food Chemistry, 2005

Eighteen triterpene saponins (1-18) from Medicago arborea leaves have been isolated and their structures elucidated by spectroscopic, spectrometric (1D and 2D NMR, FAB-MS, ESI-MS/MS), and chemical methods. They have been identified as glycosides of medicagenic, zanhic, and 2hydroxyoleanolic acids, soyasapogenol B, bayogenin, and 2 ,3 -dihydroxyolean-12-en-23-al-28-oic acid. Twelve of them, identified as 3--side}medicagenic acid (18), are reported as new natural compounds. The presence of the aldehydic group on the sapogenin moiety of saponin 10 is discussed in the framework of a possible elucidation of the biosynthesis of these metabolites.

ChemInform Abstract: 3-O-Sulfo-triterpenoid Saponins (I) from Gypsophila trichotoma Wend

ChemInform, 2009

Three new sulfated oleanane-type saponins were isolated from the roots of Gypsophila trichotoma Wend. (Caryophyllaceae). Their structures were established as 3-O-sulfoechinocystic acid 28-β -glucopyranosyl ester (1), 3-O-sulfooleanolic acid 28-β -glucopyranosyl ester (2) and 3-Osulfoquillaic acid 28-β -glucopyranosyl ester (3) on the basis of chemical and spectral evidences.

3-O-Sulfo-triterpenoid Saponins from Gypsophila trichotoma Wend

Zeitschrift für Naturforschung B, 2009

Three new sulfated oleanane-type saponins were isolated from the roots of Gypsophila trichotoma Wend. (Caryophyllaceae). Their structures were established as 3-O-sulfoechinocystic acid 28-β -glucopyranosyl ester (1), 3-O-sulfooleanolic acid 28-β -glucopyranosyl ester (2) and 3-Osulfoquillaic acid 28-β -glucopyranosyl ester (3) on the basis of chemical and spectral evidences.

Triterpenoid saponins from the roots of two Gypsophila species

Phytochemistry, 2014

Two triterpenoid saponins with two known ones have been isolated from the roots of Gypsophila arrostii var. nebulosa, and two new ones from the roots of Gypsophila bicolor. Their structures were established by extensive NMR and mass spectroscopic techniques as 3

Triterpenoid Saponins from the Roots of Glycyrrhiza Glabra

Natural Product Communications, 2019

Seven new oleanane-type triterpenoid saponins (glabasaponin A-G) were isolated from the roots of Glycyrrhiza glabra together with a known compound macedonoside A. The structures of compounds 1-7 were determined on the basis of 1D and 2D NMR as well as the MS data analyses. The sugar moieties of compound 5 were confirmed by gas chromatography after hydrolysis.