Immediate- versus controlled-release disopyramide: Importance of saturable binding (original) (raw)

Disopyramide pharmacokinetics and bioavailability

Mervyn Eadie

British Journal of Clinical Pharmacology, 1978

View PDFchevron_right

Quantitative analysis of the disopyramide concentration-effect relationship

Nick Holford

British Journal of Clinical Pharmacology, 1980

View PDFchevron_right

Determination of unbound fraction of disopyramide in plasma: a comparison of equilibrium dialysis, ultrafiltration through dialysis membranes and ultrafree anticonvulsant drug filters

Jorma Ahokas

Journal of pharmacological methods, 1982

View PDFchevron_right

Disopyramide: Serum level and arrhythmia conversion

Andreas Niarchos

American Heart Journal, 1976

View PDFchevron_right

Gas—liquid chromatographic method for the routine estimation of disopyramide in plasma or serum

Atholl Johnston

Journal of Chromatography A, 1978

View PDFchevron_right

Binding of disopyramide to α1-acid glycoprotein in plasma measured by competitive equilibrium dialysis

Jorma Ahokas

Journal of Pharmaceutical Sciences, 1984

View PDFchevron_right

Kinetics and dynamics of disopyramide and its dealkylated metabolite in healthy subjects

Karin Schenck-gustafsson

Clinical Pharmacology and Therapeutics, 1985

View PDFchevron_right

Simple high-performance thin-layer chromatography method for the determination of disopyramide and its mono-N-dealkylated metabolite in serum

Etienne Grandjean

Journal of Chromatography B: Biomedical Sciences and Applications, 1981

View PDFchevron_right

The cardiac effects of d- and l-disopyramide in normal subjects: a noninvasive study

Charles Pollick

Circulation, 1982

View PDFchevron_right

Cardiovascular Collapse Associated with Disopyramide Therapy

Rolando Gonzalez

Chest, 1981

View PDFchevron_right

Total and free disopyramide by fluorescence polarization immunoassay and relationship between free fraction and alpha-1 acid glycoprotein

Alex Pappas

Clinica Chimica Acta, 1987

View PDFchevron_right

Simultaneous analysis of disopyramide and quinidine in plasma by high-performance liquid chromatography

Jorma Ahokas

Journal of chromatography, 1980

View PDFchevron_right

?Normal? response of the QT interval and QT dispersion following intravenous injection of the sodium channel blocker disopyramide: Methodological aspects

Lennart Bergfeldt

Cardiovascular Drugs and Therapy, 1995

View PDFchevron_right

Pharmacokinetics of N-acetylprocainamide in patients profiled with a stable isotope method

David Juan

Clinical Pharmacology and Therapeutics, 1989

View PDFchevron_right

Population pharmacokinetics of pemetrexed disodium (ALIMTA) in patients with cancer

Daniele Ouellet

Cancer Chemotherapy and Pharmacology, 2000

View PDFchevron_right

Pharmacokinetic studies of DISIDA disposition

Peter Fabri

European Journal of Nuclear Medicine, 1988

View PDFchevron_right

Applied Clinical Pharmacokinetics

Brian Byrd

View PDFchevron_right

Evaluation of Pharmacokinetic and Pharmacodynamic Profiles and Tolerability After Single (2.5, 5, or 10 mg) and Repeated (2.5, 5, or 10 mg BID for 4.5 days) Oral Administration of Ivabradine in Healthy Male Korean Volunteers

Keith Wesnes

Clinical Therapeutics, 2013

View PDFchevron_right

PHARMACOKINETICS- CLINICAL PHARMACOLOGY

magendira mani vinayagam

View PDFchevron_right

Pharmacodynamic analysis of the electrocardiographic interaction between disopyramide and erythromycin in rats

HITOSHI SATO

Journal of Pharmaceutical Sciences, 1999

View PDFchevron_right

Real-World Use and Predictors of Response to Disopyramide in Patients with Obstructive Hypertrophic Cardiomyopathy

Sara Giovani

Journal of Clinical Medicine, 2023

View PDFchevron_right

Pharmacokinetics : Interactions of New Drugs and the Human Body

Barry Bleidt

Drugs and the Pharmaceutical Sciences, 1996

View PDFchevron_right

An extended pharmacokinetic/pharmacodynamic model describing quantitatively the influence of plasma protein binding, tissue binding, and receptor binding on the potency and time course of action of drugs

Dirk K F Meijer

Journal of Pharmacokinetics and Biopharmaceutics, 1996

View PDFchevron_right

PII-59Population pharmacokinetic analysis of AVP-923 (30 mg dextromethorphan and 30 mg quinidine)

Jean-Francois Marier

Clinical Pharmacology & Therapeutics, 2006

View PDFchevron_right

N-Acetylprocainamide kinetics and clinical response during repeated dosing

Roger Jelliffe

Clinical Pharmacology and Therapeutics, 1982

View PDFchevron_right

Preliminary Pharmacokinetics and Pharmacodynamics 28

Ali Najam

View PDFchevron_right

Safety, tolerability, and pharmacokinetics of the selective prostacyclin receptor agonist ralinepag in single and multiple dosing studies of an immediate‐release oral formulation in healthy volunteers

John Grundy

Pulmonary circulation, 2020

View PDFchevron_right

Variability in Response to Drugs

Mary Mihalyo

Journal of Pain and Symptom Management, 2015

View PDFchevron_right

Complementary Pharmacokinetic Measures

Krishna Devarakonda

View PDFchevron_right

Pharmacokinetic characteristics of intravenous ceftriaxone in normal adults

Alan Pollock

Antimicrobial Agents and Chemotherapy, 1982

View PDFchevron_right

Value of therapeutic drug level monitoring and unbound (free) levels

Kenny Chan

Seizure, 2008

View PDFchevron_right

Multiple Peaking Phenomena in Pharmacokinetic Disposition

Dion Brocks, Dr. Jaime A Yanez, Ph.D., Neal Davies

Clinical Pharmacokinetics, 2010

View PDFchevron_right

The influence of acidosis on the myocardial uptake and electrocardiographic effects of disopyramide

Roberto Padrini

European Journal of Pharmacology, 1989

View PDFchevron_right

Journal of Pharmacy and Pharmacology (Volume 3, Number 10) October 2015.pdf

Oksana Tryhubchak

View PDFchevron_right

Comparison of Oral and Oral Sustained-Release Rilmenidine in Healthy Volunteers and Correlation with In Vitro Sustained-Release Properties

Saco de Visser

Clinical Drug Investigation, 2001

View PDFchevron_right