Evaluation of the improvement of the clinical symptoms and spirometric indices in asthmatic patients having different treatments (original) (raw)
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Evaluation of symptoms & spirometry in children treated for asthma
Indian Journal of Medical Research, 2016
Background & objectives: Spirometry plays an important role in the assessment and long term monitoring of patients with asthma. Difficulty in performing spirometry in children has resulted in a paucity of Indian studies using spirometry regularly for research in the paediatric population. This study was undertaken to assess the clinical improvement and changes in spirometric measurements with treatment in children with newly diagnosed asthma and to compare the changes in the symptom score and spirometric measurements. Methods: This prospective study included 32 children between 6 to 12 yr of age (enrolled over a period of one year with follow up of six months) who were newly diagnosed as cases of asthma on the basis of symptoms and medical history. Baseline symptom score and spirometric measurements were determined at the first visit. The children were treated and followed up at six weeks, three and six months of initiating treatment. Symptom score and spirometric measurements were repeated at every visit. Results: Significant improvement in symptom score was evident at six weeks of therapy (P<0.05) while the lung function parameters FEV 1 (forced expiratory volume in 1 second) and FVC (forced vital capacity) showed significant improvement at three months of therapy. Peak expiratory flow rate (PEFR) was found to improve at six months. There was a positive linear correlation between the changes in symptom score and FEV 1, FVC and PEFR with treatment. Interpretation & conclusions: Symptomatic improvement became apparent before the improvement in spirometric parameters in children with asthma (after treatment initiation).
Evaluation of symptoms & spirometry in children treated for asthma
Indian Journal of Medical Research, 2016
Background & objectives: Spirometry plays an important role in the assessment and long term monitoring of patients with asthma. Difficulty in performing spirometry in children has resulted in a paucity of Indian studies using spirometry regularly for research in the paediatric population. This study was undertaken to assess the clinical improvement and changes in spirometric measurements with treatment in children with newly diagnosed asthma and to compare the changes in the symptom score and spirometric measurements. Methods: This prospective study included 32 children between 6 to 12 yr of age (enrolled over a period of one year with follow up of six months) who were newly diagnosed as cases of asthma on the basis of symptoms and medical history. Baseline symptom score and spirometric measurements were determined at the first visit. The children were treated and followed up at six weeks, three and six months of initiating treatment. Symptom score and spirometric measurements were repeated at every visit. Results: Significant improvement in symptom score was evident at six weeks of therapy (P<0.05) while the lung function parameters FEV 1 (forced expiratory volume in 1 second) and FVC (forced vital capacity) showed significant improvement at three months of therapy. Peak expiratory flow rate (PEFR) was found to improve at six months. There was a positive linear correlation between the changes in symptom score and FEV 1, FVC and PEFR with treatment. Interpretation & conclusions: Symptomatic improvement became apparent before the improvement in spirometric parameters in children with asthma (after treatment initiation).
International Journal of Contemporary Pediatrics, 2017
Background: Asthma is a disease that has become increasingly common over the last century making it now one of the commonest chronic disorders in the world. Spirometric lung function tests are playing a key role in the diagnosis and management of asthma in children. Considering the usefulness of spirometer in the diagnosis of asthma and scarcity of the literature regarding the role of spirometer in the diagnosis of Asthma especially in Indian context, the present study was undertaken to assess pulmonary function test changes in asthmatic child using spirometry and its diagnostic and prognostic value.Methods: The present study was conducted at Department of Paediatrics, Ashwini Rural Medical College, Hospital and Research Centre, Kumbhari during the study period of 2015 to 2016. Children presenting symptoms suggestive of asthma were included in the study.Results: In the present study, the commonest presentations included cough, breathing difficulty and recurrent wheeze in all the chi...
Study of spirometry parameters in suspected asthmatic children in a tertiary care hospital
International Journal of Contemporary Pediatrics, 2020
Background: Asthma in children is difficult to diagnose due to inability of young children to successfully perform spirometry. However some parameters in the spirometry which are relatively effort independent can be very helpful in confirming the diagnosis of asthma. This study was conducted to find out the most commonly affected spirometry parameter in the suspected cases of childhood asthma.Methods: Total 56 children were studied between 7 to 18 years who came for outpatient visit or admitted in the paediatric ward and were clinically suspected to be asthmatic based on asthma predictive index. They were subjected to spirometry in our institute. Baseline and post bronchodilator values of spirometry parameters were studied and analysed using standard statistical tests.Results: Baseline Forced expiratory flow between 25% and 75% of vital capacity (FEF25-75%) was found to be the most commonly affected spirometry parameter in confirming the diagnosis of suspected asthmatics and correla...
Asthma Can Present With Nonobstructive Pattern in Spirometry
CHEST Journal, 2012
PURPOSE: Asthmatic patients typically show obstructive patterns on spirometry; with positive responses to bronchodilators. In some patients, the only evidence of obstruction might be low values of forced expiratory flow (FEF), indicating inflammation within middle and small airways of the lung. However, the normal range of this parameter is very wide and it is not as reproducible as the forced expiratory volume in the first second (FEV1). On the other hand, the common practice is to exclude asthma in a symptomatic patient showing non-obstructive pattern of spirometry. This study aims to determine patterns of spirometry among patients presenting with symptoms and signs of mild to moderate asthma. METHODS: A sample of 177 known asthmatic patients (96 females and 81 males) was selected from those attending respiratory clinic of Yastabshiron Hospital in Khartoum for follow up. A portable spirometer (All flow, Clement Clarke International, UK) was used for measurement of FEV1, FVC, FEV1/FVC ratio and PEF for each patient. Measurements were carried out, according to American Thoracic Society guidelines, on presentation and then 15 minutes following inhalation of 0.5 mg salbutamol using a spacer. RESULTS: Typical obstructive pattern was found in only 26.6% of patients, normal pattern in 19.8%, restrictive in 33.3% and combined pattern in 20.3%. Significant proportions of all patterns showed positive reversibility tests (P<0.05). No correlation was found between body mass index (BMI) and patterns of spirometry. CONCLUSIONS: It is concluded that patients with mild to moderate asthma may show nonobstructive patterns in spirometry with positive response to bronchodilators. CLINICAL IMPLICATIONS: Reversibility tests should be performed for all symptomatic patients suspected of asthma, irrespective of their spirometric pattern.
Asthma symptoms do not predict spirometry
Canadian respiratory journal : journal of the Canadian Thoracic Society, 2007
Asthma is a disease characterized by variable airflow obstruction, but the measurement of airflow is often omitted in the process of diagnosis and management of the disease. Features of asthma severity and control were examined to determine the extent to which objective measurements, including forced expiratory volume in 1 s and forced expiratory volume in 1 s/forced vital capacity, correlated with other manifestations of the disease. Subjects were a consecutive sample of patients with asthma attending a university-based asthma clinic. All subjects underwent routine assessment using a standard questionnaire and spirometry. A total of 500 subjects were included in the present study, and their assessment showed that neither symptoms nor history could predict or be predicted by their measurements of lung function. Routine measurement of lung function should be performed on subjects with asthma if normal or near-normal lung function is a desired component of asthma control.
International Journal of Advances in Medicine
Background: Allergic rhinitis is predecessor of Bronchial asthma in most of the cases. Present study was aimed to understand the prevalence of the impaired spirometric changes in patients with allergic rhinitis and to find association with various demographic factors, sputum eosinophilia and eosinophil count in the blood with the impaired Spirometry of these patients.Methods: Authors conducted a cross sectional study among the patients of allergic rhinitis presented to us in our outpatient department from January 2016 to July 2017. The patient’s with allergic rhinitis either newly diagnosed or already on treatment were included in the study. Standard guidelines as given by ARIA were followed in defining a case of allergic rhinitis. The detailed clinical history was taken, and examination was performed of all the patients and documented. Spirometric evaluation was done using the standard guidelines by a desktop based Spirometry.Results: The mean age of the study subjects was 30.22±13...
Assesment of Quality Control of Spirometric Testing in Asthmatic Patients
Acta Informatica Medica, 2009
2. MATERIAL AND METODS sixty patients with bronchial asthma, according to accepted criteria were included in this study. We performed spirometric procedures for according usual protocol measuring the next parameters: Vital capacity (VC) , forced vital capacity (FVC), Forced vital capacity in first second (FEV1), FEV1%, FEV1/VC, peak flow (PF), maximal flow 75% (MF75%), maximal flow 50% (MF50%), MF25%. In any spiro metric procedures flow-volume curve was drowned. Before the spirometry medical stuff gives the explanation about procedures for anyone. All patients have been divided in two groups. The patients have been examined by two medical teams, any of them for one group of patients. The first team of medical stuff had a few year of experience, and the second one was in the beginning of this type of diagnostic procedures. The results were collected in Ms excel spreadsheet, and calculated using statistical program statistica for Windows. assess the quality control we discuss in this paper.
Study the pattern of bronchial asthma among outpatients clinic at Sohag and Akhmeem Chest Hospitals
Egyptian Journal of Chest Diseases and Tuberculosis, 2015
Background: While asthma represents a global public health issue due to high prevalence rates in the general population, several studies now indicate that the impact on public health is even more severe due to inadequate health care or the difficulty in achieving full disease control with available therapies. Aim of the work: The aim of the present study is to evaluate the pattern, risk factors, level of control and management of bronchial asthma among outpatients clinic at Sohag and Akhmeem Chest Hospitals. Subjects and methods: This study was conducted at Sohag and Akhmeem Chest Hospitals in the period between January 2011 and June 2011 and included 100 adult outpatients with bronchial asthma (BA) with a wide range of severity. Full history taking, thorough clinical examination, CXR, Peak expiratory flow (PEF), Asthma control test (ACT) questionnaire for all patients were done. Results: By using ACT, from one hundred cases of our study: 18% of cases have controlled asthma, 39% of cases have not well controlled asthma, 43% of cases have poorly controlled asthma. Tobacco smoke and infections were the most common precipitating factors to bronchial asthma. Inhalation therapy was used by 70% of the patients and MDI is the most commonly used inhalation device. Conclusions: There is need for improved asthma care in patients with moderate-to-severe asthma, including a global evaluation of asthma control, implementation of treatment plans and asthma control tests and addressing precipitating factors.
The Professional Medical Journal
Asthma is a chronic inflammatory disorder of the airways, which is associatedwith excessive airway narrowing in response to stimuli that have little or no effect on healthysubjects. Airway hyper-responsiveness with a short duration of asthma is coupled with airwayinflammation which may or may not be associated with lung impairment. Objectives: To studycorrelation of asthma duration with total anti oxidant capacity and lung function parameters.Design: Cross sectional study. Period: June 2013 to Dec 2013. Setting: Baqai MedicalUniversity and Hospital. Methodology: A total of 92 known and diagnosed cases of asthmameeting the inclusion criteria were recruited in the study. The subjects included both male andfemale with age ranging from 16-70 years. Portable handheld electronic Spirometer was usedfor performing spirometry. FRAP assay was done to measure TAC according to the method ofBenzie and Strai. Results: The mean age of patients (n-92) was 34.88±12.14 SD. The meanduration of asthma ...