Proportionality of tricuspid regurgitation determines outcome in acute heart failure (original) (raw)

European Heart Journal, 2021

Abstract

Introduction The impact of tricuspid regurgitation (TR) on outcomes in acute heart failure (AHF) incompletely understood. Often TR is considered secondary to right ventricular (RV) remodelling and dysfunction, and it is not clear if the regurgitant volume itself has additional adverse effects on outcome. We hypothesised a novel index, where TR regurgitant volumes (TRRV [ml]) are divided by the RV end-diastolic volumes (RVEDV [ml]) may help to identify patients at risk of poor outcome. Purpose To identify a cut-off for disproportionate TR and to assess its impact on survival in AHF. Methods 418 consecutive patients admitted with AHF over 12 months to a single centre in the United Kingdom were recruited and followed up for 2 years. The endpoint was death from any cause. TR RV was calculated using the proximal isovelocity surface area method and right ventricular volumes using ellipsoid model. Receiver Operator Curve analyses were carried for the TRRV/RVEDV index. The optimum cut-off f...

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