Ring transformations of 1,3-benzothiazine derivatives II conversion of 6α-aryl-7α-chloro-2,3(2′,3′-dialkqxybenzo)-1-thiaoctems3 into 2-carbomethoxy-3-aryl-7,8-dialkoxy-4.5-dihydro-1,4-benzothiazepines (original) (raw)

This research focuses on the ring transformations of 1,3-benzothiazine derivatives, particularly the conversion of 6α-aryl-7α-chloro-2,3(2′,3′-dialkoxybenzo)-1-thiaoctems3 into 2-carbomethoxy-3-aryl-7,8-dialkoxy-4,5-dihydro-1,4-benzothiazepines. Various spectral analysis methods were employed to confirm the configurations and positions of substituents, providing insight into the reaction mechanisms involved in the transformation. Further investigations on the reaction schemes continue to explore the dynamics of the benzothiazine derivatives, emphasizing the significance of substituent effects on chemical shifts and configurations.