A Clinical Study on PCOS Patients in a Tertiary Hospital (original) (raw)

An Observational Study on 100 Patients with Polycystic Ovarian Syndrome (PCOS)

Journal of Enam Medical College, 2014

Background: Women with polycystic ovarian syndrome (PCOS) have chronic anovulation and androgen excess not attributable to another cause. The fundamental pathophysiologic defect is unknown. Defects in LH secretion, LH/FSH ratio, amplitude of LH pulsations have been described; but the prevalence of these defects is not still clearly determined. Objective: To review the variable clinical presentations of polycystic ovarian syndrome. Materials and Methods: This observational study was carried out in Combined Military Hospitals of Jessore, Rangpur and Ghatail during November 2008 to June 2013. One hundred patients attending Gynaecology Outpatient Department (GOPD) having at least two of the following criteria ––hyperandrogenism, chronic oligo- or anovulation and ultrasonographic findings were selected. In all selected women LH and FSH serum levels were determined and LH/FSH ratios were calculated. Body mass index (BMI) was measured and was scored to classify their state of obesity. The ...

Characteristics of Polycystic Ovary Syndrome Polycystic (PCOS) at Soetomo General Hospital, Surabaya

Health Notions, 2019

PCOS is an endocrine disease that occurs in women of reproductive age which is characterized by several clinical manifestations such as hyperandrogen, ovarian dysfunction, and polycystic ovarian features on ultrasound examination. PCOS is an endocrine disease that is closely related to metabolic diseases such as dyslipidemia, diabetes mellitus, and hypertension. Risk factors for this disease are age, environment, genetics, body mass index (BMI), and androgen exposure. The purpose of this study is to determine the profile of PCOS in Soetomo General Hospital, Surabaya. This study used a descriptive retrospective method, using medical record data at the obstetrical clinic at Soetomo General Hospital and fertility clinic at Graha Amerta. Most patients were found in the age range of 25-44 years. Based on the diagnosis of Rotterdam criteria, the phenotype D (Oligo / Amenorrhea and SOPK on USG) was the highest phenotype. People with PCOS who did not have metabolic diseases more than those who have. The highest number of sufferers was found in the category of overweight and obese BMI, which was 35.3% each. Most PCOS sufferers were reproductive age and most have phenotype D. Most sufferers have overweight and obese BMI and do not have metabolic diseases.

Hormonal Profile of Polycystic Ovary Syndrome (PCOS) In Indian Women

2012

Hormonal profile of PCOS was studied in 102 Indian women. Serum levels of Luteinizing hormone (LH), Follicle stimulating hormone (FSH), LH:FSH ratio, Prolactin (PRL), Thyroid stimulating hormone (TSH), Dehydroepiandrosterone (DHEA), Testosterone, fasting blood glucose (FBG), fasting insulin levels and Homeostasis Model Assessment (HOMA) value were estimated. The mean LH and FSH levels are 12.54 ± 5.87 and 5.70 ± 1.80 (IU/L) respectively. The mean LH : FSH ratio is reversed and is more than two (2.23±0.94). Mean PRL, TSH, and testosterone levels show normal ranges. Mean fasting insulin (16.27±13.27 mU/ml) and HOMA (3.509±2.621) are high with 79.31% prevalence of insulin resistance. In all the patients, both LH and FSH are positively correlated with testosterone. In normal weight patients, PRL and LH: FSH are positively correlated. In overweight/obese serum LH and DHEA are positively correlated. A positive correlation is observed between testosterone and PRL in overweight/obese. On su...

Polycystic Ovary Syndrome ( Pcos ) and Related Diseases

2018

Humira Jeelani 1 , Mohd Ashraf Ganie 2 , Shajrul Amin 1 , Iram Ashaq Kawa 1 , Qudsia Fatima 1 , Zainab Drabu 3 , Fouzia Rashid 1 * 1 Department of Biochemistry/Clinical Biochemistry, University of Kashmir, Srinagar, Jammu and Kashmir, INDIA 2 Professor, Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, INDIA 3 Consultant, Gynecology & Obstetrics, Govt. Lal Ded Hospital, Srinagar, Jammu and Kashmir, INDIA REVIEW _______________________________

A Comprehensive Over View of Polycystic Ovarian Syndrome ( Pcos )

2015

INTRODUCTION: Polycystic ovarian syndrome (PCOS) was originally described in 1935 by American gynaecologistsIrving F. Stein& Michael L. Leventhal from whom the original name of SteinLeventhal Syndrome is taken, as a syndrome manifested by amenorrhoea, hirsutism and obesity associated with enlarged polycystic ovaries. PCOS is one of the most common syndromes in the modern world in women during their reproductive age. It is now recognized as a common, heterogeneous, heritable disorder affecting women throughout their lifetime. PCOS is characterized by hyperandrogenism, ovulatory dysfunction& polycystic ovaries. However, there is considerable interindividual variation in presentation. Although not required for diagnosis, the presence of insulin resistance and hyper insulinaemia is common and places those affected at increased risk of diabetes and cardiovascular disease. PCOS is a condition in which a woman has an imbalance of sex hormones. This may lead to menstrual cycle changes, cyst...

Polycystic Ovary Syndrome (PCOS): A Concerning Hormonal Condition and its Bodily Impact on Women

BioScientific Review

Polycystic Ovary Syndrome (PCOS) is a prevalent hormonal disorder that have severe health consequences for women. It arises in the early puberty stage and affects a large percentage of the world’s population. While the exact cause is unknown, it’s known to cause hyperandrogenism, insulin resistance, menstrual irregularities, and ovulatory dysfunction, all of which can lead to infertility and endometrial cancer. Long-term cardiometabolic risks and comorbidities are seen in both slim and obese PCOS patients. Given these serious implications, it’scritical to fully comprehend the pathophysiological relationships that underpin PCOS, so that better treatment plans can be developed and the standard of living for women having this condition may improve. This condition is diagnosed using three separate criteria. Rotterdam criterion is mostly utilized for PCOS diagnosis. Different symptoms of PCOS are treated in different ways. It’s imperative to comprehensively treat these patients as soon a...

Clinical, Biochemical and Hormonal Profile of Polycystic Ovary Syndrome

Journal of National Institute of Neurosciences Bangladesh, 2018

Background: The polycystic ovary syndrome is a heterogenous condition, the pathophysiology of which is multifactorial. It is considered as a systemic and metabolic disorder like hyperglycemia and insulin resistance with increased risk of type II diabetes mellitus and cardiovascular diseases.Objective: The purpose of the present study was to analyze the clinical, biochemical and hormonal profile of patients PCOS and to find out correlations among them.Methodology: This cross-sectional observational study was done including 100 diagnosed cases of PCOS attending the GOPD, BSMMU Hospital. This study was done to analyze the clinical, biochemical and hormonal characteristics of PCOS patients and to observe the correlations among them.Result: The mean age of study populations was 22.7± 6.9 years and more than half of them were overweight or obese. Menstrual abnormality like oligomenorrhoea and secondary amenorrhoea was found in 95% cases and 5% were eumenorrhic. Prevalence of hirsutism and...

POLYCYSTIC OVARY SYNDROME Polycystic Ovary Syndrome: A study from West Bengal, India

The purpose was to compare the menstrual characteristics, anthropometric and lifestyle variables between women with PCOS and healthy women matched for age in both married and unmarried categories. This cross-sectional study involved a total of 80 PCOS cases and 80 healthy controls matched for age belonging to both married and unmarried categories. Women with PCOS were identified following " Rotterdam criteria " with the help of medical practitioners from two medical hospitals in Kolkata. The unmarried controls were the students selected from schools of Konnagar, Hooghly and University of Calcutta. The married controls were selected from households of Konnagar Municipality area. The age range of the participants (case and controls) for unmarried and married were 14-33 years and 18-38 years respectively. Women with PCOS reported menstrual health problems more than controls, irrespective of marital status. Anthropometric characteristics showed that the incidence of obesity was noticeably higher among PCOS patients than controls in both married and unmarried categories. The controls were found to be engaged in physical activity more frequently than cases; however, food consumption failed to show conspicuous differences between cases and controls in both married and unmarried categories. The present study revealed significant differences in menstrual and anthropometric characteristics between PCOS patients and controls.

Case Study and Overview on Polycystic Ovary Syndrome (PCOS)

International Journal of Scientific Research in Science, Engineering and Technology, 2019

This case study is on a prominent health issue i.e. Polycystic Ovary Syndrome (PCOS) or polycystic ovary disease (PCOD). Here we are studied a 30 years woman suffering from PCOD. It was one confirmed as PCOS by consulting doctor due to irregular menstrual cycles. It is a condition that affects a woman's hormone levels. Women with PCOS produce higher-than-normal amounts of hormones. This hormone imbalance causes them to skip menstrual periods and makes it harder for them to get pregnant.