Efficacy of photodynamic therapy on candida colonization and clinical symptoms in denture stomatitis: An updated systematic review and meta-analysis (original) (raw)

Abstract

Background: Photodynamic therapy (PDT) has recently been proposed as a promising therapeutic option for Denture Stomatitis (DS). This updated systematic review and meta-analysis investigated the current evidence regarding the efficacy of PDT for DS. Materials and methods: PubMed, Scopus, Web of Science, Google Scholar, and ProQuest were searched up to June 7, 2023. All relevant clinical trials were included. RevMan software was used for meta-analysis. Results: Elven randomized clinical trials (460 DS patients) were included. Eight studies assessed the efficacy of PDT vs. topical antifungal, while three studies assessed the adjunctive use of PDT (PDT+antifungal therapy) vs. topical antifungal therapy alone. The results revealed insignificant less efficacy of PDT in comparison to topical antifungal therapy on candida colonization at 15 days (MD: 0.95, 95% CI: -0.28, 2.19, p = 0.13), but comparable results at the end of follow-up (MD: -0.17, 95% CI: -1.33, 0.98, p = 0.77). The pooled t...

Mohammed Noushad hasn't uploaded this paper.

Let Mohammed know you want this paper to be uploaded.

Ask for this paper to be uploaded.