The Dynamics of Adiponectin and Leptin on Metabolic Syndrome Patients and Age Matched Healthy Subjects (original) (raw)

2014

Abstract

The metabolic syndrome is a complex combination of interrelated risk factors of metabolic origin that, when occurring together, increase the risk of developing cardiovascular disease and diabetes. Adipocytokines are bioactive mediators released from the adipose tissue including adipocytes and other cells present at the level of fat tissues. These include several novel and highly active molecules released abundantly by adipocytes like leptin, resistin, adiponectin, as well as some more classical cytokines released possibly by inflammatory cells infiltrating fat, like tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6). The most abundantly expressed cytokines within the adipose tissue are leptin and adiponectin [1, 3]. Adiponectin, is highly expressed in adipose cells, and circulates in high concentrations in the blood. Decreased serum levels of adiponectin are associated with insulin resistance. The role of adiponectin in systemic inflammation and critical illness is not...

Carmen Barbu hasn't uploaded this paper.

Let Carmen know you want this paper to be uploaded.

Ask for this paper to be uploaded.