乳酸輸送体モノカルボン酸トランスポーター4は頭頸部扁平上皮癌における骨痛を誘発する (original) (raw)
Nippon Jibiinkoka Gakkai Kaiho, 2005
The management of metastatic squamous cell cartinoma in cervical lymph nodes from an unknown primary. Am
Haigan, 2004
Background. Metastasis from lung cancer to the spinal cord or the optic chiasm is rare. Case. A 65-year-old man was given a diagnosis as T1N2M0 localized small cell lung cancer. He responded well to systemic chemotherapy and radiotherapy. Seven months after the first admission, his brain MRI revealed multiple brain metastases, and whole brain irradiation was performed. Thirteen months after the first admission, he experienced paresis of his legs and bitemporal hemianopia. His spinal cord MRI revealed multiple intramedullary metastasis, and cerebrospinal fluid showed malignancy. Leptomeningeal metastasis from small cell lung cancer was diagnosed. Spinal cord irradiation was performed, and his lower limbs paresis improved slightly. His eyesight failed gradually, and brain MRI revealed optic chiasm metastasis. Optic chiasm irradiation was performed, but his eyesight deteriorated. Paralysis of his legs and his body gradually increased, and 18 months after the first admission, he died. Conclusion. We report a case of metastasis from small cell lung cancer to the spinal cord and the optic chiasm.
Japanese Journal of Cardiovascular Surgery, 2010
IgG4 関連疾患はさまざまな臓器に起こりうるが，多くは腺管臓器においてであり，心血管領域での報告は 少ない．今回われわれは IgG4 関連疾患による冠動脈周囲腫瘍の 1 例を経験したので報告する．症例は 69 歳 男性．胸部 CT 上，2 年前から増大し続ける，冠動脈周囲の腫瘍性病変にたいし，確定診断目的で開胸生検 術を行った．病理組織診断では線維性結合組織内に形質細胞とリンパ球の密な増生を認め，好酸球も認めら れた．全体的に線維化が目立ち，一部で肥厚した膠原線維をともなっていた．免疫染色では形質細胞の多く は IgG4 陽性であり，生検後測定した血漿 IgG4 濃度は 1,080 mg/dl と高値を示した．以上から IgG4 関連疾 患の冠動脈周囲腫瘍と診断した．心血管領域の IgG4 関連疾患は非常に稀であり，本症例は IgG4 関連疾患 による冠動脈周囲炎が腫瘍性病変を呈したものと思われた．日心外会誌 39 巻 4 号：230-233(2010) キーワード：IgG4 関連疾患，心臓腫瘍，冠動脈周囲腫瘍
Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology), 2003
We conducted a retrospective clinical study of inverted papilloma in the nose and paranasal sinuses in 26 cases (28 sides) of inverted papilloma in the last 10 years. The subjects were 17 men and 9 women with a mean age of 54.6 years. Follow-up averaged 11 months to 10.4 years with a mean of 69.4 months (5.8 years). Surgical excision is generally regarded as the treatment of choice for papilloma, however, the approach and extent of surgery have been much debated. We clarified the relationship between surgical invasion and disease recurrence. Six of 28 sides developed recurrence (21.4%) , none developed malignant transformation, and 2 of 26 cases (7.7%) were diagnosed as with bilateral papillomas. In the endoscopic group, 2 of 8 cases (25.0%) recurred, compared to 4 of 20 cases (20.0%) in the non-endoscopic group. The amount of blood lost was significantly smaller in the endoscopic group. All 8 cases with aggressive endoscopic resection manifested no recurrence and minimum blood loss. We concluded that aggressive endoscopic resection is the best treatment in terms of recurrence rate and surgical invasion. In general, this approach is preferable for tumors in the nasal cavity or in those localized with a clear endoscopic view in the paranasal sinuses.