Cyclodextrins in Chromatography. Part 1. Liquid chromatographic methods (original) (raw)

Novel stationary phases for high-performance liquid chromatography analysis of cyclodextrin derivatives

Journal of Chromatography A, 2006

Novel stationary phases were prepared for separation of cyclodextrins and cyclodextrin derivatives by bonding substituted aromatic groups (phenyl and naphthyl) to the silica gel matrix. Both the electron-withdrawing (nitro) and the hydrogen-donor/acceptor (amide or carbamide) substituents of the phenyl group play essential role in the separation of cyclodextrins and cyclodextrin derivatives. On the basis of the comparison of experimental data