Gene Transfer of Acetylcholinesterase Protects the Knockout Mouse From the Toxicity of DFP (original) (raw)

Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse

Ellen Duysen

Chemico-Biological Interactions, 2005

View PDFchevron_right

Acetylcholinesterase (AChE) gene modification in transgenic animals: Functional consequences of selected exon and regulatory region deletion

brian lamec lara de la torre

Chemico-Biological Interactions, 2005

View PDFchevron_right

Recombinant AAV-mediated gene delivery to the central nervous system

Liliane Tenenbaum

The Journal of Gene Medicine, 2004

View PDFchevron_right

Evaluating the transduction efficiency of systemically delivered AAV vectors in the rat nervous system

Olivia Yang

Frontiers in Neuroscience

View PDFchevron_right

Gene Transfer to the CNS Is Efficacious in Immune-primed Mice Harboring Physiologically Relevant Titers of Anti-AAV Antibodies

Thomas Tamsett

Molecular Therapy, 2012

View PDFchevron_right

Recombinant AAV Delivery to the Central Nervous System

Olivier Bockstael, Brian Kaspar, Kevin Foust

Methods in Molecular Biology, 2011

View PDFchevron_right

Host-regulated disposition of mammalian AChEs

Chanoch Kronman, Baruch Velan

Chemico-Biological Interactions, 2005

View PDFchevron_right

Use of Recombinant Adenovirus for Gene Transfer into the Rat Brain Evaluation of Gene Transfer Efficiency; Toxicity; and Inflammatory and Immune Reactions

Andrés Hurtado

View PDFchevron_right

AAV as a Gene Transfer Vector for the Treatment of Neurological Disorders: Novel Treatment Thoughts for ALS

Kevin Foust, Brian Kaspar

Current Gene Therapy, 2009

View PDFchevron_right

Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector

Xiao Xiao

Brain Research, 1996

View PDFchevron_right

Retargeting of adenoviral vectors to neurons using the HC fragment of tetanus toxin

Michael Themis, C. Coutelle

Gene Therapy, 2000

View PDFchevron_right

Transduction patterns in the CNS following various routes of AAV-5-mediated gene delivery

Gerard Martens

Gene Therapy, 2020

View PDFchevron_right

Adeno-Associated Viruses for Modeling Neurological Diseases in Animals: Achievements and Prospects

Evgenii Lunev

Biomedicines

View PDFchevron_right

An acidic oligopeptide displayed on AAV2 improves axial muscle tropism after systemic delivery

Marda Jorgensen, Stacy Porvasnik

Genetic Vaccines and Therapy, 2012

View PDFchevron_right

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

Giuseppe Rengo

Molecular Therapy, 2008

View PDFchevron_right

Effect of viral dose on neutralizing antibody response and transgene expression after AAV1 vector re-administration in mice

Peiyin Wang

Gene Therapy, 2008

View PDFchevron_right

Knockout of one acetylcholinesterase allele in the mouse

Arnaud Chatonnet

Chemico-Biological Interactions, 1999

View PDFchevron_right

Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System

Paul Reier

Molecular Therapy, 2004

View PDFchevron_right

Subretinal delivery of recombinant AAV serotype 8 vector in dogs results in gene transfer to neurons in the brain

Laurence Dubreil

Molecular …, 2008

View PDFchevron_right

Expression of nicotinic achetylcholine receptor subunits in ache-transgenic mice

Agneta Nordberg

Neurobiology of Aging, 2000

View PDFchevron_right

A transcription-activating polymorphism in the ACHE promoter associated with acute sensitivity to anti-acetylcholinesterases

Richard Ebstein

Human molecular …, 2000

View PDFchevron_right

A combination of mutations enhances the neurotropism of AAV-2

Caroline Bass

Virology, 2005

View PDFchevron_right

NEUROPROTECTIVE ADENO-ASSOCIATED VIRUS Bcl-X L GENE TRANSFER IN MODELS OF MOTOR NEURON DISEASE

m butler

View PDFchevron_right

Neuronal survival following remote adenovirus gene delivery

Nicholas Boulis

Journal of Neurosurgery: Spine, 2002

View PDFchevron_right

Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model

Yasunori Matsuzaki

Molecular Therapy - Methods & Clinical Development, 2014

View PDFchevron_right

Spinal Delivery of AAV Vector Restores Enzyme Activity and Increases Ventilation in Pompe Mice

Paul Reier

Molecular Therapy, 2012

View PDFchevron_right

Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons

Bas Blits, Eric Timmermans, Angelina Huseinovic

Molecular Therapy, 2010

View PDFchevron_right

Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates

Jude Samulski

Gene Therapy, 2013

View PDFchevron_right

Viral vectors for gene delivery to the central nervous system

Jude Samulski

Neurobiology of Disease, 2012

View PDFchevron_right

Systemic gene delivery to the central nervous system using Adeno-associated virus

Erwan Bezard

Frontiers in molecular neuroscience, 2014

View PDFchevron_right

Combination brain and systemic injections of AAV provide maximal functional and survival benefits in the Niemann-Pick mouse

Tatyana Taksir

Proceedings of the National Academy of Sciences, 2007

View PDFchevron_right

Position effect variegations and brain-specific silencing in transgenic mice overexpressing human acetylcholinesterase variants

H. Soreq

Journal of Physiology-Paris, 1998

View PDFchevron_right