original ) (raw )YAP1 Oncogene is a Context-specific Driver for Pancreatic Ductal Adenocarcinoma
Yaan Kang
2018
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Loss of the wild-type KRAS allele promotes pancreatic cancer progression through functional activation of YAP1
Stuart Fine
Oncogene, 2021
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Data from Dynamic Regulation of Expression of KRAS and Its Effectors Determines the Ability to Initiate Tumorigenesis in Pancreatic Acinar Cells
Luc Bouwens
2023
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Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
Jean-Christophe BRISSET
Journal of Clinical Investigation, 2012
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Dynamic Regulation of Expression of KRAS and Its Effectors Determines the Ability to Initiate Tumorigenesis in Pancreatic Acinar Cells
Luc Bouwens
Cancer Research, 2021
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YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling
monika bauden
Journal of Translational Medicine
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Down-Regulation of Yes Associated Protein 1 Expression Reduces Cell Proliferation and Clonogenicity of Pancreatic Cancer Cells
Caroline H Diep, Ph.D.
PLoS One, 2012
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Spontaneously evolved progenitor niches escape Yap oncogene addiction in advanced pancreatic ductal adenocarcinomas
Alec McIntosh
Nature Communications
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Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis
Mark Greene
Scientific reports, 2015
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Defining the KRAS-regulated kinome in KRAS-mutant pancreatic cancer
Channing Der
2021
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PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer
Seema Parte
Cell Death & Disease
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Oncogenic KRAS and the EGFR loop in pancreatic carcinogenesis—A connection to licensing nodes
Matthias Wirth
Small GTPases, 2016
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Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma
Cathy Tournier
Cancer Research, 2014
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Disruption of p16 and Activation of Kras in Pancreas Increase
wanglong Qiu
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IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation
Gwen Lomberk , Juan Iovanna
Journal of Clinical Investigation, 2014
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Abstract 3339: Modulating TAK1 expression through the inhibition of GSK3 impairs YAP/TAZ oncogenic functions in pancreatic cancer
Marco Zanotto
Cancer Research, 2018
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Oncogenic KRAS engages an RSK1/NF1 complex in pancreatic cancer
Derek Cheng
2020
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Loss of Activating Transcription Factor 3 prevents KRAS-mediated pancreatic cancer
Nawab Azizi
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GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice
Amy Lee
Proceedings of the National Academy of Sciences of the United States of America, 2017
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KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer
Channing Der
Cold Spring Harbor perspectives in medicine, 2017
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Reply to: “YAP in tumorigenesis: Friend or foe?”
amedeo columbano
Journal of Hepatology, 2015
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YAP oncogene overexpression supercharges colon cancer proliferation
Joseph Avruch
Cell Cycle, 2012
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KrasG12D induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells
Matthias Wirth
Oncogene, 2015
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YY1 suppresses proliferation and migration of pancreatic ductal adenocarcinoma by regulating the CDKN3/MdM2/P53/P21 signaling pathway
Taha Ahmad
International journal of cancer, 2017
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Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis
Shunbin Xiong
Cancer Discovery, 2021
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Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3
pankaj singh
Oncotarget, 2015
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Oncogenic KRAS signaling and YAP1/β-catenin: Similar cell cycle control in tumor initiation
Chung-jung Tsai
Seminars in cell & developmental biology, 2016
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Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo
Gloria Su
Oncotarget, 2011
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KRAS-Dependency in Pancreatic Ductal Adenocarcinoma: Mechanisms of Escaping in Resistance to KRAS Inhibitors and Perspectives of Therapy
Antonio Agostini
International Journal of Molecular Sciences
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{"__content__"=>"KRAS and TP53 Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus scrofa Pigs.", "sup"=>[{"__content__"=>"G12D"}, {"__content__"=>"R167H"}]}
Laurie Rund
Scientific reports, 2018
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Constitutively Active Akt1 Cooperates with KRasG12D to Accelerate In Vivo Pancreatic Tumor Onset and Progression
Andres Klein-Szanto
Neoplasia, 2015
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Molecular mechanisms of pancreatic carcinogenesis
Akira Horii
Cancer Science, 2006
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The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia
Michael Lotze
Proceedings of the National Academy of Sciences of the United States of America, 2012
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Cancer Cell Article EGF Receptor Is Required for KRAS-Induced Pancreatic Tumorigenesis
聖芙 黃
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