Navitoclax plus ruxolitinib in JAK inhibitor-naive patients with myelofibrosis: Preliminary safety and efficacy in a multicenter, open-label phase 2 study (original ) (raw )Real-world analysis of ruxolitinib in myelofibrosis: interim results focusing on patients who were naïve to JAK inhibitor therapy treated within the JAKoMo non-interventional, phase IV trial
Heike Pahl
Annals of Hematology
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Phase III MANIFEST-2: pelabresib + ruxolitinib vs placebo + ruxolitinib in JAK inhibitor treatment-naive myelofibrosis
Sanjay Akhani
Future Oncology
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Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis
John Mascarenhas
Haematologica, 2016
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SIMPLIFY-1: A Phase III Randomized Trial of Momelotinib Versus Ruxolitinib in Janus Kinase Inhibitor–Naïve Patients With Myelofibrosis
Timothy Devos
Journal of Clinical Oncology
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Ruxolitinib: The First FDA Approved Therapy for the Treatment of Myelofibrosis
John Mascarenhas
Clinical Cancer Research, 2012
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Use of JAK inhibitors in the management of myelofibrosis: a revision of the British Committee for Standards in Haematology Guidelines for Investigation and Management of Myelofibrosis 2012
Mary McMullin
British Journal of Haematology, 2014
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Adore: A Randomized, Open-Label, Phase 1/2 Open-Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Patients with Myelofibrosis
kate burbury
Blood, 2020
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Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial
Anita Szőke
JAMA oncology, 2018
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Robust Overall Survival and Sustained Efficacy Outcomes during Long Term Exposure to Momelotinib in JAK Inhibitor Naïve and Previously JAK Inhibitor Treated Intermediate/High Risk Myelofibrosis Patients
Daniel El Fassi
Blood, 2020
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Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial
Richard Silver
Journal of hematology & oncology, 2017
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Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis
Jordan Fridman
New England Journal of Medicine, 2010
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Beyond JAK2 Inhibitors: A Systematic Review of Management Strategies for Myelofibrosis
yasemin dede
Blood, 2018
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Results of a phase 2 study of pacritinib (SB1518), a JAK2/JAK2(V617F) inhibitor, in patients with myelofibrosis
Joy Zhu
Blood, 2015
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Clinical and molecular correlates of JAK-inhibitor therapy failure in myelofibrosis: long-term data from a molecularly annotated cohort
Hassan Sibai
Leukemia
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Development of ruxolitinib as a myelofibrosis therapy
Abdulkareem Almomen
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Next Generation Therapeutics for the Treatment of Myelofibrosis
John Mascarenhas
Cells, 2021
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Phase II trial of Lestaurtinib, a JAK2 inhibitor, in patients with myelofibrosis
Lewis Silverman
Leukemia & Lymphoma, 2019
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Managing Patients With Myelofibrosis in the Era of Janus Kinase Inhibitors
sylvia fagbemi
Journal of the Advanced Practitioner in Oncology, 2015
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Long-Term Outcome of Ruxolitinib Treatment in Patients with Myelofibrosis: Durable Reductions in Spleen Volume, Improvements in Quality of Life, and Overall Survival Advantage in COMFORT-I
Richard Silver
Blood, 2012
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BOREAS: a global, phase III study of the MDM2 inhibitor navtemadlin (KRT-232) in relapsed/refractory myelofibrosis
Dariusz Woszczyk
Future Oncology
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Efficacy and safety of ruxolitinib in the treatment of patients with myelofibrosis
Francesco Mendicino
Future oncology (London, England), 2015
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A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase 3 trials of ruxolitinib for the treatment of myelofibrosis
Nicholas Sarlis
Haematologica, 2015
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‘JAK–ing’ up the treatment of primary myelofibrosis
Rita Assi
Current Opinion in Hematology, 2017
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Long-term survival in patients treated with ruxolitinib for myelofibrosis: COMFORT-I and -II pooled analyses
Alessandro Vannucchi
Journal of hematology & oncology, 2017
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The Impact of Jak1/Jak2 Inhibitor Ruxolitinib on the Spleen Size and Symptom Burden in Myeloproliferative Diseases
sezgin etgül
International Journal of Hematology and Oncology, 2016
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Comparing the safety and efficacy of ruxolitinib in patients with Dynamic International Prognostic Scoring System low‐, intermediate‐1‐, intermediate‐2‐, and high‐risk myelofibrosis in JUMP, a Phase 3b, expanded‐access study
Pilar Giraldo
Hematological Oncology, 2021
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Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I
Richard Silver
Haematologica, 2015
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Therapeutic effects of ruxolitinib in patients with myelofibrosis without clinically significant splenomegaly
Ohad Benjamini
Blood, 2012
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Safety and efficacy of CYT387, a JAK1 and JAK2 inhibitor, in myelofibrosis
Aref Al-kali
Leukemia, 2013
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Looking forward: novel therapeutic approaches in chronic and advanced phases of myelofibrosis
John Mascarenhas
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program, 2015
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Revised assessment of response and long-term discontinuation rates among 111 patients with myelofibrosis treated with momelotinib or ruxolitinib
Ramy Abdelrahman
Leukemia, 2014
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The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis
Richard Silver
British Journal of Haematology, 2013
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Biology and Clinical Management of Myeloproliferative Neoplasms and Development of the JAK Inhibitor Ruxolitinib
J Mariano Anto Bruno Mascarenhas
Current Medicinal Chemistry, 2012
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Analysis of predictors of response to ruxolitinib in patients with myelofibrosis in the phase 3b expanded-access JUMP study
Catherine Bouard
Leukemia & Lymphoma, 2020
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Ruxolitinib in the treatment of patients with myelofibrosis — questions and answers
Marta Sobas
Oncology in Clinical Practice
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