Gas Chromatography. Mass Spectrometry Analysis of 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Urine and Feces (original) (raw)

Validation in rats of two biomarkers of exposure to the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP): PhIP-DNA adducts and urinary PhIP

Marlin Friesen

1996

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2-Amino-1-methyl-6-(5-hydroxy-)phenylimidazo[4,5-b]pyridine (5-OH-PhIP), a biomarker for the genotoxic dose of the heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Henrik Frandsen, Hanne Frederiksen

Food and Chemical Toxicology, 2002

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Identification of urine metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans

Cyndy Salmon

Carcinogenesis, 2000

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Excretion of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine and 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline, PhIP- dG, PhIP-DNA and DiMeIQx-DNA from the rat

Henrik Frandsen

Carcinogenesis, 1997

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Intestinal absorption and cell transforming potential of PhIP-M1, a bacterial metabolite of the heterocyclic aromatic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Leonie von Elsner

Toxicology Letters

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N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

J. Alexander

Carcinogenesis, 2000

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Effect of diet on serum albumin and hemoglobin adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans

Domenico Rotilio, Cinzia Magagnotti

International Journal of Cancer, 2000

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Metabolism of the Food Mutagen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]pyridine (PhIP) in Isolated Liver Cells from Guinea Pig, Hamster, Mouse, and Rat

Jørn Holme

Environmental Health Perspectives, 1994

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Concentration of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) in urine and alkali-hydrolyzed urine after consumption of charbroiled beef

Paul Strickland

Cancer Letters, 2001

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Differential Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine (PhIP) in Mice Humanized for CYP1A1 and CYP1A2

Jeffrey Idle

Chemical Research in Toxicology, 2005

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Intestinal bacteria metabolize the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans

L. Vanhaecke

Food and Chemical Toxicology, 2008

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Measurement of the Heterocyclic Amines 2-Amino-9H-pyrido[2,3-b]indole and 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Urine: Effects of Cigarette Smoking

Joni Jensen

Chemical Research in Toxicology, 2015

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PhIP metabolites in human urine after consumption of well-cooked chicken

Cyndy Salmon

Journal of Chromatography B, 2004

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Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes

André Guillouzo

Carcinogenesis, 2002

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Liquid chromatography-mass spectrometry method for the analysis of 1,4-dimethylpyridinium in rat plasma - application to pharmacokinetic studies

Kamil Kus

Biomedical Chromatography, 2013

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The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods

Mitsuru Futakuchi

Cancer research, 1997

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2-Amino-1-methyl-6-phenylimidazo [4,5- b ]pyridine (PhIP) in human hair as biomarker for dietary exposure

Åshild Andreassen

Biomarkers, 1999

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Immunoaffinity Purification of Dietary Heterocyclic Amine Carcinogens

Tanya Djanegara

Environmental Health Perspectives, 1993

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Organ dependent enhancement of rat 3,2'-dimethyl-4-aminobiphenyl (DMAB) carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): positive effects on the intestine but not the prostate

Mitsuru Futakuchi

Carcinogenesis, 2001

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Metabolism of the Food-Associated Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine by Human Intestinal Microbiota

Arne Heyerick

Journal of Agricultural and Food Chemistry, 2006

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Biomarkers of exposure to heterocyclic amines: approaches to improve the exposure assessment

Solfrid Hegstad, Henrik Frandsen, Kristian Ingebrigtsen

Food and Chemical Toxicology, 2002

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Dose validation of PhIP hair level as a biomarker of heterocyclic aromatic amines exposure: a feeding study

Robert Turesky

Carcinogenesis, 2016

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Alternative biomarkers of n-hexane exposure: Characterization of aminoderived pyrroles and thiol-pyrrole conjugates in urine of rats exposed to 2,5-hexanedione

M. Batoréu, Maria Bronze

Toxicology Letters, 2014

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Organ differences in the enhancing potential of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on carcinogenicity in the prostate, colon and pancreas

Mitsuru Futakuchi

Mutation research, 2002

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SPE–GC/FTD determination of N-methyl-2-pyrrolidone and its metabolites in urine

Masanori Ogawa

Journal of Chromatography B, 2007

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Spectrophotometric determination of pyrrole-like substances in urine of rat and man: An assay for the evaluation of 2,5-hexanedione formed fromn-hexane

Johannes G Filser

Archives of Toxicology, 1990

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Liquid-chromatographic determination of 4-aminopyridine in serum, saliva, and urine

William Ravis

Clinical chemistry, 1981

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Analytical characterization and rapid determination of 2-(diphenylmethyl)pyrrolidine in blood and application to an internet product

derrick pounder

Journal of Chromatography B, 2011

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Incorporation of the Food Mutagen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP) into Fur and Correlation with Intestinal Tumourigenesis in Min/+ Mice

REI REI

Pharmacology and Toxicology, 2003

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