Primary intrapulmonary benign schwannoma. A case with ultrastructural and immunohistochemical confirmation (original) (raw)

A case report of intrapulmonary schwannoma

General thoracic and cardiovascular surgery, 2014

A 38-year-old man without any symptoms was admitted to our institution because of an abnormal shadow found incidentally on a chest X-ray. Chest computed tomography showed a round mass in the lingular segment of the left upper lobe. Lingular segmentectomy was performed, and the histopathological diagnosis was intrapulmonary schwannoma. Immunohistochemical staining revealed a positive result for S-100 protein and negative results for CD34 and desmin. We report this case of intrapulmonary schwannoma, which is extremely rare.

Intranodal thoracic schwannoma, an unusual type of neurogenic tumor

General Thoracic and Cardiovascular Surgery, 2011

The primary intranodal schwannoma is an uncommon variant of schwannomas and extremely rare. We report the case of a 70-year-old woman who was found to have a soft tissue opacity in the right hemithorax on chest posteroanterior radiography and signifi cant uptake of 18 F-fl uorodeoxyglucose on positron emission tomography. We performed thoracoscopic resection, and a defi nitive diagnosis of intranodal schwannoma was made from the pathological fi ndings.

Oversized primary intrapulmonary schwannoma: A case report and a review of the literature

Surgical Neurology International

Background: Schwannomas, also known as neurilemommas, are benign, well-circumscribed encapsulated peripheral nerve sheath tumors with rather indolent evolution. Made up of cells closely related to normal myelinating Schwann cells, these neoplasms may arise from the peripheral nervous system as well as from spinal or cranial nerves. They are mostly found in the base of the skull, neck, chest wall, posterior mediastinum, posterior spinal roots, cerebellopontine angle, retroperitoneum, and flexor surfaces of the extremities. The incidence rate of spinal schwannoma is 0.3–0.5/100,000 cases per year with an average age of 50 at diagnosis. We report a case of intrapulmonary schwannoma, adding a review of the literature. Case Description: A 20-year-old female patient with no significant medical history, presented with pleuritic chest pain, shortness of breath, right upper limb weakness, and numbness. A computed tomography of the chest and magnetic resonance imaging showed a 7.2 × 10.5 × 8....

Primary endobronchial schwannoma

2010

Primary intrabronchial neurilemmas, also called schwannomas, are extremely rare tumors that originate from Schwann cells. We report a case of intrabronchial schwannoma arising in the left main bronchus in an 8-year-old child. The diagnosis was made by bronchofiberscopic biopsy. Although the tumor was benign, the patient was subjected to left pneumonectomy because of destruction of the pulmonary parenchyma distal to the obstruction. The diagnosis of intrabronchial schwannoma was supported pathologically with characteristic findings on Antoni A and Antoni B areas. This case is unique in that it is the youngest case in the literature.

Schwannoma of the Pulmonary Artery

Schwannoma (neurilemmoma) originating from the pulmonary artery has not before been described. A 65 year-old male presented with dyspnoea on exertion. CT scan was negative for pulmonary thromboembolism, but showed a well circumscribed, heterogeneous mass, 52 mm × 45 mm × 41 mm, straddling the left pulmonary artery and compressing the left atrium. The mass was found at surgery to be originating from the lateral wall of the left pulmonary artery. The tumour was completely resected, and the pulmonary artery reconstructed. The mass was found to be a benign schwannoma on histopathology.

Tracheal Schwannoma: An Uncommon Entity

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2018

A 34-year-old lady presented with breathlessness for one and half year, cough with expectoration for five months, two episodes of haemoptysis three months back, pain in right side of chest for two months. She was a mother of four children, all born with normal vaginal delivery. Physical examination revealed decreased chest movements and air entry on right side, wheeze on exertion and mild First biopsy revealed necrotic tissue only. Repeat rigid bronchoscopic biopsy revealed squamous cell carcinoma with necrotic tissue. Surgery was planned keeping in mind the second biopsy report. Surgery was done with right posterolateral thoracotomy in 4th intercostal space. Tumour had widened the tracheal diameter to approximately 5cm and the tumour had extended from carina to right main bronchus. Trachea was cut longitudinally with a sleeve at carinal level. Tumour along with a sleeve of trachea was excised with adequate margins. Tumour was polypoidal in nature. As the lung was almost completely destroyed by long standing obstructive pneumopathy, pneumonectomy was done. The longitudinal tracheal ostomy was closed in two layers with prolene 5 0 and buttressed with a pleural patch. This trachea was still admitting 7Fr endotracheal tube. Hilar lymph nodal dissection was completed. The distracted ribs were approximated and sutured with non-absorbable polyamide sutures. Chest was closed in standard fashion with insertion of intercostal chest tubes [Table/Fig-2]. Patient was electively ventilated till next morning. Postoperative convalescent period was uneventful and she was discharged on 10th day. Postoperative histopathology report [Table/Fig-3] showed tumour composed of spindle cells with wavy nuclei, forming hypo and hypercellular areas with Verocay bodies; Surface showing mucosal ulceration, squamous metaplasia with focal dysplasia and dense