Left Atrial Myxoma Causing Mitral Valve Obstruction with Right Ventricular Dysfunction Complicated by Atrial Fibrillation (original) (raw)
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Pulmonary Artery Hypertension and Related Complications Associated to Left Atrial Myxoma
The open cardiovascular medicine journal, 2017
Atrial Myxoma (AM) is a primary benign tumour of the heart that may behave in a not so benign manner causing serious cardiac and systemic complications [1-4]. The global annual incidence of AM is 0.5 per million people and may occur in different locations within the heart cavities but primarily affect the left atrium in 75% of the cases [5-7]. There have been reports of myxoma in the right atrium and in the left or right ventricles [8, 9]. The symptoms may widely differ depending on several factor related to the mass itself. AM tends to differ in shape, size, and texture, and originate from the vicinity of the fossa ovalis in the inter-atrial septum. AM occurs in patients between the ages of 30 and 60 years, but it can be seen at any age [7]. Sometimes, AM is discovered incidentally while investigating nonspecific symptoms on a routine echocardiography. Most AM are isolated, and they present in familial cases in less than 10%.
Giant left atrial myxoma mimicking severe mitral valve stenosis and severe pulmonary hypertension
International Archives of Medicine, 2013
Myxoma is the most common primary tumor of the heart and can arise in any of the cardiac chambers. This paper reports A 50 -year-old woman without medical history and any cardiovascular risk factors was hospitalized for exertional dyspnea and palpitations from three months and signifiant weight loss. Transthoracic echocardiogram showed a giant left atrial myxoma mobile confined to the left atrium in systole, in diastole the tumor was seen prolapsing across the mitral valve into the left ventricle and partially obstructing it and causing severe functional mitral stenosis with a mean gradient of 21,3 mmHg. Severe pulmonary hypertension was confirmed by Doppler PAPs =137 mmHg. The patient was scheduled for cardiac surgery with good outcome.
International Journal of the Cardiovascular Academy, 2016
Myxomas are the most frequently seen benign cardiac tumor. They mostly originate from interatrial septum. They can lead variable signs and symptoms. Opposite to their benign structure, embolic and obstructive complications can be fatal. Myxomas can rarely lead acute myocardial infarction due to coronary embolism. In this article, we presented a left atrial myxoma case that originated from posterior mitral annulus with simultaneous acute inferoposterior myocardial infarction, severe pulmonary hypertension and dynamic mitral stenosis. The patient was managed with successful percutaneous transluminal coronary angioplasty of the left circumflex artery without stenting and surgical removal of the myxoma consecutively. Pulmonary hypertension dropped significantly in postoperative follow-up.
Mitral valve recurrence of a left atrial myxoma
European Journal of Cardio-Thoracic Surgery, 2002
Recurrence of intracardiac myxoma is unusual, and heart valves are extremely rare locations for this tumor to originate, either as the primary site or the site of recurrence. We present a case of non-familial cardiac myxoma, which after successful resection of the tumor mass from the left atrium, recurred in the atrial surface of anterior leaflet of the mitral valve, along with a review of similar cases in the literature. Myxoma was originally believed to recur due to inadequate resection, but recent data suggest the multicenteric disease to be the reason. Mitral valve myxoma mainly presents with symptoms of embolization and appears to affect women more often. It involves both leaflets with the same frequency and usually originates from the atrial side. Transesophageal echocardiography is the gold standard for non-invasive diagnosis and localization. Operative resection of the tumor along with the underlying tissue followed by suture repair of the valve and annuloplasty is recommended as the most appropriate treatment option. Long-term follow-up of patients by echocardiography is advised for early detection of any recurrence.
The Heart Surgery Forum, 2014
Myxomas comprise 50% of all benign cardiac tumors in adults, with the right atrium as their second most frequent site of origin. Surgical resection is the only effective therapeutic option for patients with these tumors. The association between right atrial myxomas and severe left ventricular systolic dysfunction is extremely rare and makes treatment even more challenging. This was the case for our patient, a 47-year-old male with a right atrial mass and a severely impaired left ventricular function, with a 20% ejection fraction. Global enlargement of the heart was also noted, with moderate right ventricular dysfunction. The tumor was successfully excised using the on-pump beating heart technique, with an immediate postoperative improvement of the left ventricular ejection fraction to 35%. The technique proved useful, with no increased risk to the patient.