Umbrella-like helical structure of alpha-synuclein at the air-water interface observed with experimental and theoretical sum frequency generation spectroscopy
Steven Roeters
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A structural and kinetic link between membrane association and amyloid fibril formation of α-Synuclein
Henrike Heise
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Conformational Behavior and Aggregation of α-Synuclein in Organic Solvents: Modeling the Effects of Membranes
Larissa Munishkina
Biochemistry, 2003
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Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation
boran uluca
Communications Biology, 2018
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Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering
Emma Sparr
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Caught in action: Interfacial and amyloid protein conformation revealed with vibrational spectroscopy
Steven Roeters
2018
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Molecular Simulations of the Fluctuating Conformational Dynamics of α-Synuclein
Corey Ohern
Biophysical Journal, 2013
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Simultaneous IR-spectroscopic observation of α-synuclein, lipids, and solvent reveals an alternative membrane-induced oligomerization pathway
Karin Hauser
Chembiochem : a European journal of chemical biology, 2017
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Dynamic molecular exchange and conformational transitions of alpha-synuclein at the nano-bio interface
Davide Prosperi
International Journal of Biological Macromolecules, 2020
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Conformational equilibria in monomeric alpha-synuclein at the single molecule level
Massimo Sandal
2007
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Amyloid oligomerization of the Parkinson's disease related protein α-synuclein impacts on its curvature-membrane sensitivity
Jose Ignacio Gallea
Journal of neurochemistry, 2018
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A Relationship between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-Synuclein and β-Synuclein
Robert Clay Rivers
Biochemistry, 2014
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Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils
Emma Sparr
Journal of Physical Chemistry Letters, 2019
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Two Different Binding Modes of α-Synuclein to Lipid Vesicles Depending on its Aggregation State
Johannes Levin
Biophysical Journal, 2012
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Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
Emma Sparr
Proceedings of the National Academy of Sciences of the United States of America, 2016
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The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils
riza dervisoglu
Nature Communications
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Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein
Anthony Braun
Biochimica et biophysica acta, 2016
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A Coarse-Grained Molecular Dynamics Approach to the Study of the Intrinsically Disordered Protein α-Synuclein
Yong Joo
Journal of Chemical Information and Modeling, 2019
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Time-Resolved FRET Detection of Subtle Temperature-Induced Conformational Biases in Ensembles of α-Synuclein Molecules
Elisha Haas
Journal of Molecular Biology, 2011
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Effect of Electric Field on α-Synuclein Fibrils: Revealed by Molecular Dynamics Simulations
Jamoliddin Razzokov
International Journal of Molecular Sciences
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Small Molecules Attenuate the Interplay between Conformational Fluctuations, Early Oligomerization and Amyloidosis of Alpha Synuclein
amrita kundu
2017
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Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level
Massimo Sandal
PLOS Biology, 2008
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Adsorption of α-synuclein to supported lipid bilayers: positioning and role of electrostatics
Michael Haertlein
ACS chemical neuroscience, 2013
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Insights into the molecular mechanism of amyloid filament formation: Segmental folding of α-synuclein on lipid membranes
riza dervisoglu
Science Advances, 2021
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Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity
Luigi Bubacco
Quarterly Reviews of Biophysics, 2014
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From The Cover: Release of long-range tertiary interactions potentiates aggregation of natively unstructured -synuclein
Carlos Bertoncini
Proceedings of The National Academy of Sciences, 2005
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Structures and free energy landscapes of the wild-type and A30P mutant-type α-synuclein proteins with dynamics
Isin Tuna Sakallioglu
ACS chemical neuroscience, 2013
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