Cerebral venous thrombosis demonstration with magnetic resonance angiography (original) (raw)
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Role of MRI in Evaluation of Cerebral Venous Thrombosis
To evaluate the MR findings of cerebral venous sinus thrombosis using T1W, T2W, FLAIR, DWI, SWI and MR Venogram. A study of 70 patients were carried in the Department of Radio-diagnosis, Deccan college of medical sciences, Hyderabad. Patients from all the age groups including both men and women & confirmed by MRI & MRV were included. Patients who were initially diagnosed as CVT but MRI,MRV were normal, with MR incompatible devices or implants ,with claustrophobia were excluded. In my study Of 70 cases , higher age of occurrence is 25-32,more commonly seen in females in puerperal period with 25 cases ,with common clinical presentation headache , seizure , focal neurological deficit. In my study common sinus thrombosis in combination occurred are superior sagittal thrombosis 40 cases , transverse sinus thrombosis 26 cases , followed by sigmoid sinus thrombosis 20 cases. parenchymal haemorrhage better detected in T1/T2 flair , SWI evaluated additional findings venous congestion , micro haemorrhages , MRV detected all cases in my study. MRI with MRV is extremely helpful in accurate detection of CVT. It also differentiates from cytotoxic and vasogenic oedema. swi helps in detecting micro haemorrhages , clot. Acute stage venous thrombus is iso intense or hypo intense on T1WI and hypo intense on T2WI may be difficult to diagnose on conventional MR imaging. MRV is useful in this stage with pronounced thrombosis detection. MRI with MRV is a very helpful imaging modality in detection of cerebral venous sinus thrombosis. MRI features of superficial T2 hyper intense lesions, intra parenchymal haemorrhage has highest accuracy. SWI useful during the acute phase of CVT. Venous hypertension can be detected at an early stage in CVT showing venous congestion. MRV has the highest accuracy in diagnosing Cerebral venous thrombosis.
Experimental Cerebral Venous Thrombosis: Evaluation Using Magnetic Resonance Imaging
Journal of Cerebral Blood Flow and Metabolism, 1996
Diffusion-weighted (DWI), dynamic contrast enhanced (perfusion imaging), and conventional spin-echo magnetic resonance imaging (MRI) were applied to character ize the pathophysiology of cerebral venous thrombosis (CVT) in the rat. We induced CVT by rostral and caudal ligation of the superior sagittal sinus (SSS) and injection of a thrombogenic cephalin suspension. The resulting pathology was monitored in an acute and long-term study group. Evans blue and hematoxy Iin-eosin staining was performed for comparison with MRI data. A subgroup of animals was treated with i.v. tissue plas minogen activator (t-PA). Successful thrombosis of the SSS was confirmed by macropathology or histopathology in all rats. Parenchymal lesions as shown by MRI, however, were present only in animals with additional involvement of cortical cerebral veins (II of 18 rats). The early pathology was clearly detected
Imaging of cerebral venous thrombosis
Diagnostic and interventional imaging, 2014
Cerebral venous thrombosis (CVT) is a potentially life-threatening emergency. The wide ranging of clinical symptoms makes the use of imaging in "slices" even more important for diagnosis. Both CT and MRI are used to diagnose the occlusion of a venous sinus, but MRI is superior to CT for detecting a clot in the cortical or deep veins. CT can show the hyperintense clot spontaneously and CT angiography the intraluminal defect. MRI also detects this thrombus, whose signal varies over time: in the acute phase, it is hypointense in T2*, whilst T1 and T2 can appear falsely reassuring; in the subacute phase, it is hyperintense on all sequences (T1, T2, FLAIR, T2*, diffusion). MRI easily shows the ischemic damage, even hemorrhagic, in the cerebral parenchyma in cases of CVT. Finally, imaging may reveal pathology at the origin of the CVT, such as a fracture of the skull, infection, tumor, dural fistula, or intracranial hypotension.
Neuroimaging of Cerebral Venous Thrombosis (CVT) – Old Dilemma and the New Diagnostic Methods
Polish Journal of Radiology, 2015
Background: Cerebral venous thrombosis is a relatively uncommon neurologic disorder that is potentially reversible with prompt diagnosis and appropriate medical care. The pathogenesis is multifactorial and the disease may occur at any age. CVT is often associated with nonspecific symptoms. Radiologists play a crucial role in patient care by providing early diagnosis through interpretation of imaging studies. Underdiagnosis or misdiagnosis can increase the risk of severe complications, including hemorrhagic stroke or death. The purpose of this study is to investigate radiological and clinical characteristics of cerebral venous thrombosis (CVT) based on material from 34 patients under care of our hospital. Material/Methods: A total of 34 patients were diagnosed with CVT from August 2009 until March 2015. A clinical and radiological database of patients with final diagnosis of CVT was analyzed. Results: Patient group included 22 women and 12 men at a mean age of 48.7 years (ranging from 27 to 77 years). In the study group 8 patients (23.5%) suffered from hemorrhagic infarction, whereas 16 patients (47%) were diagnosed with venous infarction without hemorrhage. Thirty patients (88%) had transverse sinus thrombosis.
MRI of Clot in Cerebral Venous Thrombosis: High Diagnostic Value of Susceptibility-Weighted Images
Stroke, 2006
Background and Purpose-In cerebral venous thrombosis (CVT), the sensitivity of conventional MRI sequences to detect clot in the sinuses or veins is incomplete and largely depends on the time elapsed since thrombus formation. Little is known concerning the corresponding diagnostic value of fluid-attenuated inversion recovery (FLAIR), echo-planar T2* susceptibility-weighted imaging (T2*SW) or diffusion-weighted images (DWI). Methods-We performed a retrospective analysis of 114 MRI examinations from 39 patients with CVT using a structured assessment. The time course of sensitivity in the detection of clot (nϭ166 clots) was analyzed for different MR sequences using a multilevel logistic model. The sensitivity of different MR sequences for diagnosis of cortical venous thrombosis was tested separately (nϭ38 clots). Results-The sensitivity of T2*SW and T1-weighted spin echo image (T1SE) sequences to detect clot in the sinuses or veins was estimated at 90% and 71% between day 1 and day 3, which was much higher than that of T2SE, FLAIR or DWI during the first week of clinical onset. The sensitivity of T2*SW was stable in the first week. After this period, the sensitivity of T2*SW decreased less than that of T1SE. Thrombosed cortical veins, even in the absence of visible occlusion on magnetic resonance venography, were detected more frequently with T2*SW (97%) and T1SE (78%) than with FLAIR or DWI (Ͻ40%). Conclusions-T2*SW imaging appears to be of additional diagnostic value in CVT. The T2*SW sequence may be particularly useful during the acute phase of CVT when the sensitivity of the other sequences is incomplete and for the diagnosis of isolated cortical venous thrombosis. (Stroke. 2006;37:991-995.)
MR Imaging Features of Isolated Cortical Vein Thrombosis: Diagnosis and Follow-Up
American Journal of Neuroradiology, 2008
BACKGROUND AND PURPOSE: To our knowledge, very few MR imaging data have been reported in isolated cortical venous thrombosis (ICoVT). The purpose of this study was to describe MR imaging features, including T2*gradient-echo (GE) sequence, in presumed ICoVT. MATERIALS AND METHODS: MR imaging examinations were performed in 8 patients with ICoVT (MR venography was performed in all patients and digital substraction angiography in 4) at the time of diagnosis and during the follow-up at 15 days (4 patients) and at 3 (8 patients), 6 (6 patients), 12 (3 patients), and 18 months (1 patient). We assessed the presence of a magnetic susceptibility effect (MSE) on T2*GE imaging at each site of cerebral venous thrombosis and the presence or absence of a normal flow void and iso-, hypo-, or hyperintense signal intensity on T1, T2, diffusion-weighted imaging (DWI), and fluid-attenuated inversion recovery (FLAIR) images. Parenchymal signal-intensity changes were also assessed on the same sequences.
Cerebral venous thrombosis: diagnosis dilemma
Neurology International, 2011
Cerebral venous thrombosis is increasing common disease in daily practice with sharing clinical nonspecific symptoms. This disorder is potentially lethal but treatable, oftenly it was overlooked in both clinical and radiologic in routine practice. Whenever, clinical suspected, prompt investigation by noninvasive imaging such as conventional technique of CT, MR or advanced modilities such as CTV, MRV will helpful in prompt diagnosis and treatment. These imaging modalities may reveal either direct sign( visualization of intraluminal clot) and indirect signs ( paranchymatous change, intracranial hemorrhage). By using of effective treatment will improve the prognosis of the patient. This review summarizes insights into etiology, incidence, imaging modalities and current of the treatment.
Advances in Clinical and Experimental Medicine, 2017
Background. Cerebral venous thrombosis (CVT) is a rare condition which constitutes 0.5-1% of all strokes. The clinical and radiological picture of CVT is non-specific and can mimic other disorders. Objectives. The aim of the study was to retrospectively evaluate and correlate clinical and radiological symptoms presented by patients with CVT, both in the initial and follow-up neurological and neuroimaging examinations, with a special emphasis on diagnostic difficulties. Material and methods. Material consisted of 11 patients with CVT (7 women, 4 men). The average age was 43.5, ranging from 23 to 69 years. Clinical symptoms, laboratory findings, risk factors and the results of neuroimaging examinations including CT, MRI and DSA were retrospectively analyzed and correlated. Results. All subjects developed superficial CVT and 1 also deep CVT, with no parenchymal lesions in 2 cases, non-hemorrhagic infarctions in 3 and hemorrhagic lesions in 6 subjects. The most frequent symptoms were headache, seizures and hemiparesis. The major risk factors were hormonal therapies in women and congenital thrombophilia. Factors influencing the clinical course and outcome the most were location and type of brain lesions, with hemorrhagic cortical infarctions bringing the worst prognosis and being associated with the highest rate of persistent neurological deficits, despite the rate of vessel recanalization. Conclusions. In our opinion, quick diagnosis before parenchymal hemorrhagic lesions are visible on CT is of crucial importance and requires a constant alertness and good cooperation of neurologists and radiologists, especially in emergency settings.
Imaging of Cerebral Venous and Sinus Thrombosis
Neurovascular Imaging, 2014
Early and correct diagnosis of cerebral venous and sinus thrombosis (CVST) is necessary for prompt management of this disorder. Neuro-imaging is a crucial part of diagnosis of CVST. I reviewed the findings of non-enhanced computerized tomography (CT), Contrast enhanced CT, CT venography (CTV), different techniques of magnetic resonance imaging (MRI), MR venography, and digital subtraction angiography. I also reviewed the potential pitfalls in image interpretation. [GMJ.2016;5(Supp.