Figure S5 from CRISPR Screening Identifies WEE1 as a Combination Target for Standard Chemotherapy in Malignant Pleural Mesothelioma (original) (raw)

AI-generated Abstract

This study presents data on the characterization of malignant pleural mesothelioma (MPM) cells that develop resistance to standard chemotherapy, specifically highlighting the response of both parental and chemotherapy-resistant cell lines to combination treatment with cisplatin and pemetrexed. The results underscore a significant difference in cell viability between resistant and parental MPM cells, confirmed through viability assays and clonogenic assays, emphasizing the need for alternative therapeutic strategies targeting resistance mechanisms.

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Figure S5 from CRISPR Screening Identifies WEE1 as a Combination Target for Standard Chemotherapy in Malignant Pleural Mesothelioma (original) (raw)

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