An Efficient Synthesis of the Taxane-Derived Anticancer Agent ABT-271 (original) (raw)

Preface, Brief History of the Discovery and Development of Taxane Anticancer Agents ( 1-3 )

Iwao Ojima

ACS Symposium Series, 1994

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A ready synthesis of intermediates containing the A-ring substructure of taxol: a Diels-Alder route to the B-seco taxane series. [Erratum to document cited in CA117(3):26833h]

William Bornmann

J Org Chem, 1993

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ChemInform Abstract: New Strategy for the Synthesis of the Taxane Diterpenes: Formation of the BC-Rings of Taxol via a (5 + 2) Pyrylium Ylide-Alkene Cyclization, Ring Expansion Strategy

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Synthetic studies on taxane diterpenes X-ray structure of a key intermediate

Isaac Hanna

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Evaluation of 2-Bromocyclohexenone Acetals as Vehicles for the Introduction of C-7 Oxygen Preliminary to the Synthesis of Taxane Diterpenes

Francis Montgomery

The Journal of Organic Chemistry, 1995

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A convergent synthesis of functionalized B-seco taxane skeletons

Christian Montalbetti

Tetrahedron Letters, 1995

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A ready synthesis of intermediates containing the A-ring substructure of taxol: a Diels-Alder route to the B-seco taxane series

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The Journal of Organic Chemistry, 1992

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Taxol Semisynthesis: A Highly Enantio- and Diastereoselective Synthesis of the Side Chain and a New Method for Ester Formation at C-13 Using Thioesters

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Second Generation Taxanes: from the Natural Framework to the Challenge of Drug Resistance

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A Novel Hydroxylation Step in the Taxane Biosynthetic Pathway: A New Approach to Paclitaxel Production by Synthetic Biology

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Taxane diterpenes 5: Synthesis of the A- and C-rings: An unusual rearrangement of an N-hydroxyimino lactone

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Facile access to the ABC ring system of the taxane diterpenes via anionic oxy-Cope rearrangements

James White

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The Chemistry of the Taxane Diterpene: Stereoselective Reductions of Taxanes

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Site-specific enzymatic hydrolysis of taxanes at C-10 and C-13

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Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model

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Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors

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