Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life (original) (raw)

Journal of Geriatric Psychiatry and Neurology

Abstract

Objective To explore the effects of a multicomponent training (MT) physical exercise intervention in the cognitive function, neuropsychiatric symptoms, and quality of life of older adults with major neurocognitive disorder (NCD). Methods Quasi-experimental controlled trial. Thirty-six individuals (25 female) were equally distributed to an exercise group (aged 74.33 ± 5.87 years) or a control group (aged 81.83 ± 6.18 years). The Alzheimer’s Disease Assessment Scale – Cognitive (ADAS-Cog), the Neuropsychiatric Inventory (NPI) and the Quality of Life – Alzheimer’s Disease (QoL-AD) tests were performed before and after the intervention. Results There was no clear interaction effect factor of intervention on ADAS-Cog (B = 1.33, 95% CI: -2.61 – 5.28, P = .513), NPI (B = −8.35, 95% CI: −18.48 – 1.72, P = .115), and QoL-AD (B = 2.87, 95% CI: .01 – 5.73, P = .058). Conclusions The 6-month MT physical exercise intervention did not present evidence of slowing down cognitive decline neither imp...

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