A case of extensive ischemic stroke due to primary systemic amyloidosis (original) (raw)

Silent stroke and related risk factors

Journal of Gorgan University of Medical Sciences, 2013

Background and Objective: The silent brain infarctions are common in first-ever stroke. Some recent studies show the possible role of silent brain infarction in ischemic stroke. The aim of this study was to evaluate the frequency of silent brain infarction in acute first-ever ischemic stroke and its association with stroke risk factors. Materials and Methods: This descriptive-analytical study was carried out on 203 (94 males, 109 females) patients with acute first-ever ischemic stroke in Shafa hospital in Kerman, Iran during 2010. The diagnosis of ischemic stroke was made by physical examination and was confirmed by MRI and CT Scan. A questionnaire containing demographic information and risk factors including hypertension, diabetes, hyperlipidemia, cigarette smoking, ischemic and non-ischemic heart disease for stroke as well as presence of silent stroke was completed for each patient. Data were analyzed using SPSS-16 and logistic regression test. Results: The mean age of patients was 62.56±17.35 years. Among our patients history of hypertension, hyperlipidemia, cigarette smoking, diabetes, history of ischemic heart disease, history of other cardiac disease and silent stroke were observed in 66 (32.5%), 26 (12.8%), 16 (7.9%), 40 (19.7%), 27 (13.3%), 16 (7.9%) and 31 (15.3%), respectively. The probability of silent stroke among patient with hyperlipidemia, was 3.7 times more than those without hyperlipidemia (95%CI: 1.556-12.780, P<0.05). There was no significant correlation between silent stroke and the above risk factors. Conclusion: Silent stroke was found in 15% of patients with ischemic stroke. Control of hyperlipidemia can have a vital role in the prevention of silent stroke.

Parasagittal Meningioma: A mimic of Cerebrovascular Accident

Journal of Mazandaran University of Medical Sciences, 2012

Meningomas is usually a benign, encapsulated tumor with a predominance in women. Parasagittal Meningomas is a common type of these tumors and with clinical manifestation like Cereberovascular diseases. This is a report on 80-year-old female patient with acut presentations of a parasagittal meningiomas with apoplexy of tumor and subcoma and right hemiplegia, that resected totally in the Behshar Imam Khomeini Hospital (August 2011).

Evaluation of the Serum Melatonin Levels in the Treatment of Patients with Multiple Sclerosis

Arak Medical University Journal, 2018

Background: Multiple sclerosis (MS) is a myelinating inflammation and an impairment of neuronal cell regeneration in the central nervous system with unknown causes. The aim of this study was to evaluate serum melatonin levels in the treatment of patients with multiple sclerosis. Materials and Methods: A prospective study and a Cohort were conducted on 40 MS patients with multiple sclerosis patients referring to instituate MS in Arak city for one year. In this study, patients who were treated with interferon-moderating drugs and who had not been treated for more than one year were randomly selected. A questionnaire containing demographic information and clinical information and separation of interacting factors was completed and completed. Clinical information included MRI, VEP, EDSS (Expanded Disability Status Scale) score, and clinical symptoms. The patients also received peripheral blood samplers 3 times in 6 months intervals to measure melatonin and their melatonin levels, and th...

Computational Analysis of Asymmetric Arterial Stenosis with Applications of Fluid-Solid Interaction

IFMBE Proceedings, 2007

Arterial stenosis and the consequent cardiovascular diseases such as atherosclerosis remain the major cause of mortality in the world. In this study, blood flow was analyzed in a three-dimensional model of stenosed carotid artery with asymmetric stenosis utilizing fluid-structure interaction method. The modeling was performed by ANSYS finite element software. To overcome the software inconsistency in FSI mode, a new code was designed in ANSYS multi-physics environment for coupling of solid and fluid domains via incremental boundary iteration method. The results indicated a considerable variation of local blood pressure, velocity and shear stress in stenosed artery, high pressure drop along stenosis, compressive stress and larger flow separation zone in the post-stenotic region as the result of increased eccentricity of stenosis. The results might be applied in evaluation of plaque severity, progression of disease, plaque growth and vulnerable regions of plaque to fracture.

ارزش بررسي‌هاي عصب روان‌شناختي در تشخيص پيش‌رس زوال عقل

Neuropsychological studies have demonstrated that preclinical dementia accompanies a decreasing trend in cognitive state a few years prior to clinical diagnosis. Sudden decline in episodic memory and semantic knowledge have been found to have the capability to differentiate patients in preclinical state of dementia from those experiencing normal aging. In addition, decline in episodic memory is usually the earliest cognitive change that occurs prior to the development of clinical dementia syndrome. Asymmetry in cognitive abilities may also occur in this preclinical phase of the disease and predict imminent dementia. This review summarizes the contributions of neuropsychological assessment in early diagnosis of dementia.

Serum Folate Levels in Major Beta Thalassemia Patients

2008

Objective: Beta major thalassemia is a variant of beta thalassemia syndrome which could be treated with bone marrow transplantation or if not available, regular blood transfusion. In the latter case, supportive therapy is the mainstay of treatment because of low folate intake or absorption. But the main cause of insufficient supportive therapy is the increasing need of bone marrow for ineffective erythropoiesis in the absence of regular blood transfusion. The purpose of regular blood transfusion in β major thalassemia patients is to maintain the range of hemoglobin level between 9 and 11 gr/dl to stop insufficient erythropoiesis completely. Therefore, by regular blood transfusion, supportive therapy with folic acid would not be needed. The aim of this study is to determine serum folate level in regular transfused β major thalassemia patients in Mofid Children's Hospital during 2006.