Comparative flavonoids content of Taraxacumofficinale vegetal organs extracts from different Romanian regions (original) (raw)
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Annals of the Academy of Romanian Scientists Series on Biological Sciences
In the biomedical sciences field of recent years, phytotherapeutic products usage has intensified because they are a safe and sustainable alternative, with less environmentally aggressive molecules that are able to meet therapeutic needs. Mature vegetal product Taraxacum sp., also known as dandelion, has been used for hundreds of years as a traditional remedy for liver, kidney, lung, gastric diseases and even some cancers, due to its anti-inflammatory and antioxidant effects. The aim of this paper was to assess the contents of some bioactive principles and overall antioxidant potential of Taraxacum sp. hydroalcoholic extracts obtained from both plant organs, herba and radix. The vegetal product was collected in the period September-October 2021, from spontaneous flora of South Dobrudja area, Romania. Fresh plant was dried at room temperature on metal sieves, grind to a fine powder and extracted 10% concentration in ethanol 50% and 70% concentrations, using cold maceration and Soxhle...
A comprehensive review of the benefits of Taraxacum officinale on human health
Bulletin of the National Research Centre, 2021
Background Taraxacum officinale (G.H. Weber ex Wiggers), commonly known as dandelion, is a herbaceous plant native to North America, Europe and Asia. This plant has been used for health purposes since ancient times. The phytochemicals present in different parts of the plant are responsible for its medicinal properties. In this review, we describe the main health properties of Taraxacum officinale. Main body of the abstract We searched for the main medicinal properties of Taraxacum officinale in the scientific literature, using the PubMed database. We selected 54 studies and we described twelve therapeutic properties, which are reported in previous studies. These properties are diuretic, hepatoprotective, anticolitis, immunoprotective, antiviral, antifungal, antibacterial, antiarthritic, antidiabetic, antiobesity, antioxidant and anticancer effects. We also found that the most frequently reported therapeutic effects include hepatoprotective, antioxidant and anticancer activities. Sho...
Molecules, 2020
Dandelion (Taraxacum officinale L.) roots, leaves, and flowers have a long history of use in traditional medicine. Compared to the above organs, dandelion fruits are the least known and used. Hence, the present paper was aimed at the phytochemical analysis of T. officinale fruit extract and estimating its antiradical, antiplatelet, and antioxidant properties related to hemostasis. Methanolic extract of fruits (E1), enriched with polyphenols (188 mg gallic acid equivalents (GAE)/g), was successfully separated into cinnamic acids (E2; 448 mg GAE/g) and flavonoids (E3; 377 mg GAE/g) extracts. Flavonoid extract was further divided into four fractions characterized by individual content: A (luteolin fraction; 880 mg GAE/g), B (philonotisflavone fraction; 516 mg GAE/g), C (flavonolignans fraction; 384 mg GAE/g), and D (flavone aglycones fraction; 632 mg GAE/g). High DPPH radical scavenging activity was evaluated for fractions A and B (A > B > Trolox), medium for extracts (Trolox >...
Literature Review on The Biological Effects of Taraxacum Officinale Plant In Therapy
Asian Journal of Pharmaceutical Research and Development, 2019
Since human beings have sought in nature, components that can obtain help in therapeutics or even in the cure of diseases. The progress made in the area of science promoted the development of recognized and effective herbal medicines, as well as the search for the population, for less aggressive treatments. The evaluation of the antioxidant activity of plants has been an important issue taking into account its importance on human health, since the natural antioxidants present a reduced health risk, when compared to the synthetic ones that present toxic effect. From the Asteraceae family, of which the plant species Taraxacum officinale, popularly known as dandelion, stands out among the 71 species on the list of the Ministry of Health (RENISUS), scientifically affirmed, to treat liver disorders, inflammations, potential in the anti-bacterial, cytotoxic, antiviral, antiparasitic, antifungal activity, besides studies to verify its anticancer action and of carcinogenic prevention. The acute toxicity of Taraxacum officinale appears to be low, with LD50 values estimated at 36.8g / kg and 28.8g / kg, for the whole plant. The adverse or complex toxic effects for T. officinale have not yet been reported. This review of the literature was elaborated through studies of articles contained in the Scielo, Google Scholar and Pub Med platforms. Through this review the importance of phytotherapy studies for pharmacological purposes was verified, aiming to improve the therapeutics.
International Journal of Molecular Sciences, 2025
Taraxacum officinale (dandelion) is a perennial flowering plant of the Asteraceae family that has spread globally and is well-known for its traditional uses. The aim of this work is to provide a detailed review of scientific literature on the genus Taraxacum from the last two decades, with particular emphasis on the biological and pharmacological characteristics of dandelions. The traditional use of Taraxacum species and their potential use in medicine are assessed. In addition, individual papers describing principal pathways and molecules modulated by Taraxacum in antitumoral, anti-inflammatory, antidiabetic, hepatoprotective, immunomodulatory, antimicrobial, and antioxidant activities are presented. This review of phytochemical studies reveals that dandelions contain a wide range of bioactive compounds, such as polyphenols, phytosterols, flavonoids, carotenoids, terpene, and coumarins, whose biological activities are actively explored in various areas of human health, some constituents having synergistic activities, including antioxidant, antimicrobial, anti-inflammatory and anticancer activities. The study provides a screening of Taraxacum sp. chemical composition, an assessment of the main pharmacological properties, and a description of relevant studies supporting the use of dandelion for its particularly valuable and diversified therapeutic potential in different diseases.
Taraxacum officinale: a high value less known medicinal plant
Annals of Plant Sciences, 2014
The family Asteraceae, best represented by the species of Taraxacum officinale , is known world wide for its manifold uses. It is widely used to cure kidney disease, swelling, skin problems, heart burn, eye inflammation, bone fractures, diabetes mellitus, hypertension, gastrointestinal complaints, warts, liver/gallbladder problems, hepatitis B, cancer, etc., and widely used in modern medicine. Therefore, an attempt has been made to assess the medicinal potential of the species both in traditional and modern medicine system. This paper provides the relevant information about medicinal properties of the high value medicinal plants. Further, we have tried to compile all the possible information regarding the medicinal potential of this plant. So far only limited scientific studies have been conducted on this plant. So further research is required to highlight the potential of the plant.
Molecules
This experiment was conducted with extracts prepared from dandelion (Taraxacum officinale F. H. Wigg) leaves and flowers, using the micelle-mediated extraction method, with the surface active compound Triton X-100 and water–acetone as the extraction solvents. Extracts were, first, examined for the content of total phenols and the antioxidant capacity. All extracts showed good anti-radical properties, especially for leaves, in comparison to the flower samples. Flavonoids (mainly luteolin derivatives) and phenolic acids, predominated among the determined polyphenols. Quantitative analyses indicated acetone extract to be the richest in phenols (up to 0.535 mg/mL), in the case of dandelion leaves, and Triton X-100 extract in the case of flowers (0.385 mg/mL). Extracts were also evaluated for cytotoxicity to the model cell line (epithelial rabbit kidney cells RK13), using the colorimetric 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) test and the real-time cell anal...
Standardization of roots of Taraxacum officinale
Environment Conservation Journal
Taraxacum officinale (Dandelion) belongs to the Asteraceae family; an edible herb commonly found in subtropical and temperate regions worldwide. Traditionally dandelion is used in diarrhea, gout, jaundice, diabetes, pneumonia, urinary problems and to purify the blood. The phytochemical study of dandelion discovered the occurrence of β- sitosterol, stigmasterol, taraxsterol, lactucopicrin, lactucin, cichorin, taraxacoside, taraxacerin, campesterol, homotaraxasterol, etc. Anti-inflammatory, immunostimulating, antimicrobial, antioxidant and antidiabetic activities of dandelion were studied. This plant has great therapeutic value and in order to overcome the problem of adulteration, the present study was aimed to standardize and preserve the quality parameters of the plant. Roots of Taraxacum officinale were subjected to measurements including macroscopy, microscopy, foreign organic content, ash value, extractive value, phytochemical screening, fluorescence analysis and chromatographic ...
Polyphenols Content and Antioxidant Activities of Taraxacum officinale F.H. Wigg (Dandelion) Leaves
International Journal of Pharmacognosy and Phytochemical Research 2014-15; 6(4); 889-893 ISSN: 0975-4873 , 2014
Plant of genus Taraxacum known as dandelion have long been used in tradition medicinal. Extracts from dandelion possess anti-influenza virus, anti-fertility and anti-retrovirus activity, antioxidant and hepatoprotective effects. Chicoric acid also known as dicaffeyltartaric acid and belongs to phenylpropanoids is one of the main constituent of T. officinale. The current investigation was conducted to determinate the total polyphenols and total dihydroxycinnamic derivatives contents, and to evaluate the antioxidant capacities in aqueous and ethanol-water extracts prepared from T. officinale leaves. Total phenolic content was determined by using the Folin-Ciocalteau method. The antioxidant capacities in the forms of DPPH, FRAP and CuPRAC were evaluated by spectrophotometric methods. The results indicated that TPC, chicoric acid concentration, DPPH, FRAP and CuPRAC values were higher in 50% ethanol extract of T. officinale leaves: 33.90 ± 0.57 mg GAE/ g DW, 3.1 g/ 100g DW, 136.3 mM TE/ g DW (DPPH method), 131.5 mM TE / g DW (FRAP method) and 407.8 mM TE/ g DW (CuPRAC method). The results clearly demonstrated the Taraxacum officinale F.H. Wigg leaves are rich source of polyphenols possess high antioxidant properties. The high yield of cichoric acid make this plant valuable source of commercial production.
Estimating Total Phenolics in Taraxacum officinale (L.) Extracts
Polish Journal of Environmental Studies, 2018
This study focuses on evaluating total phenolic contents (TPC) in Taraxacum officinale (L.), a member of the family Asteraceae (compositae). The TPC were estimated by Folin-Ciocalteu's reagent and gallic acid was taken as standard. The amount of phenolics was communicated as gallic acid equivalent (GAE). The TPC varied from 41.47 mg/g to 691.6 mg/g in the Taraxacum officinale (L.) extracts. The maximum phenolic contents were found in hydro-alcoholic extract (691.6 mg/g GAE) in comparison with aqueous extract. These extracts have a significant role as antibacterial and antimicrobial agents.