Mouse and pig nonviral liver gene therapy: success and trials (original) (raw)

Gene Ther Mol Biol, 2005

Abstract

Summary Success has been achieved with nonviral gene delivery to mouse liver, resulting in long-term therapeutic plasma levels of human α-1 antitrypsin (hAAT) protein, employing the hydrodynamic procedure. Now we contribute to explore the mechanism involved in the successful procedure, with the aim of circumventing the existing serious limitations for application to clinical practice. The results from mouse hydrodynamic gene

Salvador Aliño hasn't uploaded this paper.

Let Salvador know you want this paper to be uploaded.

Ask for this paper to be uploaded.