A Study of Outcome of Noninvasive Ventilatory Support in Acute Respiratory Failure (original) (raw)
Indian Journal of Respiratory Care
Respiratory failure is said to exist when there is inadequate gas exchange due to dysfunction of the respiratory system. [1] Ventilatory support is an important treatment component of patients having acute respiratory failure. It can be invasive or noninvasive. To avoid the morbidity associated with endotracheal intubation, noninvasive ventilation (NIV) was developed. NIV has been highly successful in acute respiratory failure caused by a wide spectrum of diseases. NIV decreases work of breathing, improves arterial oxygenation and alveolar ventilation, prevents the use of invasive mechanical ventilation, reduces the incidence of ventilator associated pneumonia, and decreases the length of intensive care unit (ICU) stay and mortality, mainly due to chronic obstructive pulmonary disease (COPD) exacerbations [2,3] and acute cardiogenic pulmonary edema. [4-7] However, NIV is not successful in all patients with acute respiratory failure. NIV has controversial role in respiratory failure due to pneumonia and Acute Respiratory Distress Syndrome (ARDS). [8] Patients on NIV must be monitored closely for signs of treatment failure and should be intubated promptly before a crisis develops. Therefore, there is a need to identify prognostic factors for the outcome of NIV. [9-11] Aim of the study The aim of the study was to assess the outcome of NIV in patients of acute respiratory failure and to determine predictors of positive outcome. PatIents and Methods It was an observational and analytical type of study. A total of 110 patients admitted to our hospital from January 2011 to
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