Correlation of Helicobacter pylori in dental plaque and gastric mucosa of dyspeptic patients (original) (raw)
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Helicobacter pylori in dental plaque and gastric mucosa: correlation revisited
JPMA. The Journal of the Pakistan Medical Association, 2008
Helicobacter pylori (H. pylori) related gastric infection is highly prevalent in developing countries. Prevalence of bacterium in dental plaque from these regions is also reported to be high, but association between simultaneous colonization of H. pylori in both these sites has not been established yet. Aim of this paper is to review possible association between simultaneous oral and gastric H. pylori colonization in dyspeptic patients. Pertinent literature was reviewed and all available evidence collected from Medline and PakMedinet. Studies conducted in the developing world show conflicting results. Some report a positive relation between oral and gastric H. pylori colonization while others deny any association. This may be due to the population sampled or methodology applied. Further studies are recommended to confirm the association between concurrent presence of H. pylori in dental plaque and gastric mucosa of dyspeptic patients using sensitive and specific tests for detection ...
Concomitant Colonization of Helicobacter pylori in Dental Plaque and Gastric Biopsy
Journal of Pathogens, 2014
Frequently reported H. pylori antimicrobial therapy failures suggest that there might be a different niche where the bacteria can stay safe. Current study aims to examine potential role of oral colonization of H. pylori to feed reinfection after primary therapy. However, patients who were admitted to the gastroscopy section were chosen and gastric biopsy and dental plaque specimens were collected. Molecular and biochemical tests were applied to confirm H. pylori identity in different colonization niches. Results showed that 88.8% of dyspeptic patients had epigastric pains with nocturnal awakening when they were hungry ( = 0.023). All patients who received therapy already were again H. pylori positive while they are still carrying H. pylori in dental plaque ( = 0.001). Moreover, H. pylori infection was sought in 100% of gastric biopsy's dyspeptic patients who had ulcerated esophagitis and erosive duodenitis and who were H. pylori positive, and 75% of dyspeptic patients with duodenum deformity had this bacterium in gastric biopsies ( = 0.004). Present study showed that only successful eradication of gastric H. pylori cannot guarantee prevention of reinfection. Conclusively, a new strategy which indicates concomitant eradication in oral and gastric colonization can result in clearance of H. pylori infection.
2010
Objective and Background The aim of this study was to analyze whether there is any association between dental plaque, oral hygiene and periodontal disease and Helicobacter pylori gastric infection. H.pylori, a spiral shaped microaerophilic bacterium, is responsible for peptic ulcer diseases, gastritis and gastric malignancies. Among various reports on the transmission of H. pylori, the faecal oral and oraloral routes have been suggested to be the most plausible ones. Although it may be transmitted through the oral cavity, it is unknown whether the dental plaque acts as a permanent reservoir of H. pylori. Methods In this case control study, 124 dyspeptic patients with dyspepticsymptoms were categorized into the cases (60) and the controls (64) on the basis of the rapid urease test (RUT) and the histopathological results of the antral biopsy specimens. Patients with either of the tests positive or with both the tests positive were categorized as the cases and those with both the tests negative were taken as the controls. Results A high prevalence of H. pylori in dental plaque was found among the cases than in the controls. Among the cases, 52 patients out of the 60 (86.6%), had a positive rapid urease test in the dental plaque and among the controls, 12 out of 64 (18.75%) showed positive results. A highly significant association was found between poor oral hygiene status and periodontal disease (probing pocket depth) with H.pylori infection. Conclusion Triple / quadruple therapy has no effect on plaque associated H.pylori and it may continue to act as a reservoir. Plaque control measures and pocket eradication therapy are highly beneficial in eliminating and preventing the colonization of H.pylori in the oral cavity.
Quintessence international (Berlin, Germany : 1985), 2001
It has been suggested that the oral cavity and dental plaque might be a reservoir for Helicobacter pylori (Hp). In this study, our aims were to detect the prevalence of Hp colonization in dental plaque and tongue scrapings of patients with chronic gastritis and to investigate the effect of systemic treatment upon this colonization and eradication of Hp from gastric mucosa. Eighty-one patients (49 men, 32 women) were included in the study. Dental plaque and tongue scraping specimens were obtained and assessed with Campylobacter-like organism (CLO) test, prior to endoscopic examination. By endoscopy, 2 antral and 1 corpus biopsy samples were taken for histologic examination, and 1 antral biopsy sample was taken for CLO test examination. Chronic gastritis was diagnosed in 63 (77.7%) of 81 patients. Dental plaque samples of 64 (79%) patients and tongue scraping samples of 48 (59.2%) patients were urease positive. Of the 63 patients with chronic gastritis, dental plaque and tongue scrapi...
amtsibiu.ro
Helicobacter pylori detection in oral cavity has lead to the question whether it has a significant importance for the local pathology or for the gastro-intestinal tract. Multiple research conducted in the last twenty years have certified that H. pylori exists in the dental plaque, saliva, aphthous ulceration (RAU), but controversy still exists regarding their contribution as a principal infection or reinfection factor at the gastric level of these reservoirs of Helicobacter. The implications in local pathology seem to be especially in parodontal disease and the pathology of the mucosa.
Helicobacter Pylori in the Dental Plaque
International Journal of Medical and Dental Sciences, 2014
The oral cavity has been suggested as a reservoir of Helicobacter pylori, but the assumption that the oral microflora may be a permanent reservoir is still controversial. Objective: The aim of this work is to see if the plaque can be a reservoir of H. Pylori based on data from clinical study and literature. Materials and Methods: 35 patients were recruited; oral bacterial samples were taken from patients before performing endoscopy and gastric samples. These samples underwent microbiological and histological examination with bacterial identification. Results: In periodontal samples, the urease test was positive in 33 of 35 patients, whereas no culture was positive. In gastric biopsies, the Urease test was positive for 20 samples from 35, the culture showed that the bacterium was present in 16 of the 35 patients, the Urease test and culture was positive for 15 samples from 35. On histological examination, 22 samples were positive among 35. Conclusion: Whatever the role of the oral cavity (transient or permanent reservoir of H. Pylori), a support dental and periodontal case is essential in all patients with H. Pylori in the stomach.Prescribing antibiotics for the eradication of H. Pylori in the stomach does not allow disposal at the dental biofilm; Mechanical disruption of the latter by scaling and root planing is essential.