Impact of Sleep Apnea Treatment Compliance on Cardiovascular Health Outcomes: A Quantitative Analysis of Adherence to CPAP Therapy and Its Effects on Cardiovascular Metrics (original) (raw)
2022, International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences
Impact of Sleep Apnea Treatment Compliance on Cardiovascular Health Outcomes Objective: To investigate the relationship between adherence to Continuous Positive Airway Pressure (CPAP) therapy and improvements in cardiovascular health outcomes in patients with obstructive sleep apnea (OSA). Methods: A cross-sectional study was conducted with 50 OSA patients using CPAP therapy for at least six months. Participants were categorized into low, moderate, and high adherence groups based on average nightly CPAP usage. Cardiovascular outcomes, including systolic and diastolic blood pressure, lipid profile (total cholesterol, LDL, HDL, and triglycerides), and incidence of cardiovascular events, were assessed. Statistical analyses included multiple regression and correlation analysis to evaluate associations between adherence levels and cardiovascular metrics. Results: Higher CPAP adherence was significantly associated with lower systolic and diastolic blood pressure (p < 0.01). Participants with high adherence had significantly lower LDL cholesterol compared to those with low adherence (p = 0.03), while total cholesterol approached significance (p = 0.05). HDL cholesterol and triglycerides did not show significant differences across adherence levels (p = 0.08 and p = 0.07, respectively). The incidence of cardiovascular events was lower in the high adherence group (p = 0.04). Conclusion: Adherence to CPAP therapy is positively associated with improved cardiovascular health outcomes, including lower blood pressure, better lipid profiles, and reduced incidence of cardiovascular events. These findings emphasize the importance of enhancing patient adherence to CPAP therapy to achieve better cardiovascular health in OSA patients.
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