Progress in research on ligands, nuclides and techniques for labeling monoclonal antibodies (original) (raw)

Labeling of monoclonal antibodies with radionuclides

Seetharama Acharya

Seminars in Nuclear Medicine, 1989

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Chelating polymer modified monoclonal antibodies for radioimmunodiagnostics and radioimmunotherapy

Ban-an Khaw

Journal of Controlled Release, 1993

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Antibody labeling with radioiodine and radiometals

Maneesh Jain

Methods in molecular biology (Clifton, N.J.), 2014

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Development of a stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer

Mark Hylarides

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989

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Radiolabeling of Antibodies

William Eckelman

Cancer Research, 1980

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Methods for Radiolabelling of Monoclonal Antibodies

Vladimir Tolmachev

Methods in Molecular Biology, 2013

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Immunochemical aspects of monoclonal antibodies important for radiopharmaceutical development

Stanley Mills

International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1986

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Aminooxy���functionalized DOTA for radiolabeling of oxidized antibodies: evaluation of site���specific 111In���labeled trastuzumab

Parasuraman Padmanabhan

2012

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Development of a Model System to Evaluate Methods for Radiolabeling Monoclonal Antibodies

Robert Nicolotti

Journal of Nuclear Medicine, 1984

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Preparation of 105Rh Labeled Monoclonal Antibody (MAb B72.3) Using Aminobenzylpropyleneamineoxime as the Bifunctional Chelating Agent; Comparison to 131I Labeled MAb B72.3

Alan Ketring

Radiochimica Acta, 1999

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A biological method to evaluate bifunctional chelating agents to label antibodies with metallic radionuclides

Yasushi Arano

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994

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Synthesis and evaluation of novel bifunctional chelating agents based on 1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-tetraacetic acid for radiolabeling proteins

Markus Beitzel

Nuclear Medicine and Biology, 2003

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Antibody labeling with copper-67 using the bifunctional macrocycle 4-[(1,4,8,11-tetraazacyclotetradec-1-yl)methyl]benzoic acid

Helmut Maecke

Bioconjugate Chemistry, 1991

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Bifunctional aryliodonium salts for highly efficient radioiodination and astatination of antibodies

Jean-François Gestin

Bioorganic & Medicinal Chemistry, 2017

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The preparation of DTPA-coupled antibodies radiolabeled with metallic radionuclides: an improved method

a najafi

Journal of Immunological Methods, 1983

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Recent developments in monoclonal antibody radiolabeling techniques

Ronnie Mease

OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information), 1989

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Yttrium-90-Labeled Monoclonal Antibody for Therapy: Labeling by a New Macrocyclic Bifunctional Chelating Agent

David Kukis

Journal of Nuclear Medicine Official Publication Society of Nuclear Medicine, 1990

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Radioiodination of internalizing monoclonal antibodies using N-succinimidyl 5-iodo-3-pyridinecarboxylate

Craig Reist

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Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the 64Cu-Labelling of Immunoconjugates

Sophie Levesque

Molecules

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Direct radiolabeling of monoclonal antibodies with rhenium-188 for radioimmunotherapy of solid tumors — a review of radiolabeling characteristics, quality control and in vitro stability studies

Normando Iznaga

Applied Radiation and Isotopes, 2001

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Direct Procedure for the Production of 211At-Labeled Antibodies with an -Lysyl-3-(Trimethylstannyl)Benzamide Immunoconjugate

Sofia H L Frost, Tom Bäck

Journal of Nuclear Medicine, 2008

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Radiolabelling of monoclonal antibodies: Optimization of conjugation of DTPA to F(ab?) 2-fragments and a novel measurement of the degree of conjugation using Eu(III)-labelling

Pirkko Vihko

European Journal of Nuclear Medicine, 1989

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Synthesis and preliminary evaluation of a new chelate N2S4 for use in labeling proteins with metallic radionuclides

Alan Epstein

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, 1991

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Enhanced Target-Specific Accumulation of Radiolabeled Antibodies by Conjugating Arginine-Rich Peptides as Anchoring Molecules

Yasushi Arano

Bioconjugate Chemistry, 2010

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Chemical design of radiolabeled antibody fragments for low renal radioactivity levels

Yasushi Arano

Cancer research, 1999

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Technetium-labeling of monoclonal antibodies with functionalized BATOs: 2. TcCl(DMG)3CPITC (CPITC=carboxyphenylisothiocyanate) labeling of B72.3 and NP4 whole antibodies and NP4 F(ab')2

david Nowotnik

Bioconjugate Chemistry, 1991

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Assessment of the Radiochemical Design of Antibodies with a Metabolizable Linkage for Target-Selective Radioactivity Delivery

Yasushi Arano

Bioconjugate Chemistry, 1998

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Production of radiolabeled monoclonal antibody conjugates by photoaffinity labeling

Alan Ketring

1990

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Determination of the immunoreactive function of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess

Frank Cuttitta

Journal of Immunological Methods, 1984

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New approaches to delivering metal-labeled antibodies to tumors: Synthesis and characterization of new biotinyl chelate conjugates for pre-targeted diagnosis and …

Oliver Renn

Journal of controlled …, 1996

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In vivo evaluation of a lead-labeled monoclonal antibody using the DOTA ligand

David Colcher

European Journal of Nuclear Medicine and Molecular Imaging, 1998

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Site-specific conjugation of a radioiodinated phenethylamine derivative to a monoclonal antibody results in increased radioactivity localization in tumor

André Pèlegrin

Journal of Medicinal Chemistry, 1993

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Monoclonal Antibodies Labeled with Rhenium-186 Using the MAG3 Chelate: Relationship between the Number of Chelated Groups and Biodistribution Characteristics

Roel Van Der Schors

Journal of Nuclear Medicine

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p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging

Garry Kiefer

European Journal of Nuclear Medicine and Molecular Imaging, 2009

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Feasibility of the radioastatination of a monoclonal antibody with astatine-211 purified by wet extraction

Jean-François Gestin

Journal of Labelled Compounds and Radiopharmaceuticals, 2008

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