FNAC AS PREOPERATIVE DIAGNOSTIC TOOL FOR NEOPLASTIC AND NON-NEOPLASTIC BREAST LESIONS: A TEACHING HOSPITAL EXPERIENCE (original) (raw)
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IOSR Journals , 2019
Background: The diagnosis of breast lump is very important for achieving best result, it needs multidisciplinary approach, it include triple assessment-Clinical, Radiological and Pathological examination is gold standard technique for diagnosis of breast diseases, the present study was analyze the effectiveness of FNAC in detecting breast diseases. FNAC of Breast Lump is basic and important, minimal invasive diagnostic tool pre-operatively for early and accurate diagnosis, & has ability to give rapid diagnostic information high correlation to that of frozen Section, hence it reduced need of frozen section biopsy meanwhile both aspirator and interpreter should be the same person with adequate sample. Cytological study carried out as per the worldwide accepted five tier system. Aims & objective: 1.To Asses Variant of Breast Lump. 2. To Asses Diagnostic Accuracy and Adequacy of Sample. 3. Cytological features of Smear. Material & Methods: This is a Prospective Study, from October 2016 to October 2018,(2 years) carried out at Tertiary care hospital and Ayush path Laboratory, Dhule Maharashtra, India. Inclusion Criteria: Young females with breast lump, age group ranges from 15 to 35 years. Exclusion Criteria: Male gynaecomastia, Females with age > 35years. Procedure: FNAC was performed after taking written informed consent with all aseptic precaution, patient were given proper position as it helps considerably for insertion of needle accurately without technical aids with 23-24 G Needle and plastic syringe, with multidirectional aspiration of Sample and adequacy was defined Results: This study including 85 cases and 91 breast lump requested for FNAC. Lump in breast is the commonest presentation, followed by Pain, Commonly reporting age group was 21-25years, seen in 29 cases (34.13%). Commonly observed lump size was 2-4 cm, 55 lump (60.43%), and Commonest site of breast lump is Upper Outer Quadrant in 34 cases (37.36%), maximum breast lump specified in C2 cytological category it is Benign specific Category 73 sample (80.21%) & highest diagnosed lump is Fibroadenoma 60 lump (69.78%). Conclusion:-Diagnosis of breast diseases by Triple assessment-clinical radiological and pathological examination is gold standard technique, FNAC is the least invasive diagnostic tool for benign breast diseases as a part of high diagnostic accuracy, less-time consuming, affordable, less patient discomfort, provision of multisampling therefore FNAC should be used as a routine method for determining the nature of breast lump.
Correlation of Fnac and Histological Diagnosis in the Evaluation of Breast Lumps
Journal of University Medical & Dental College, 2020
Objective: To correlate the cytological findings of breast lumps with their histomorphological diagnosis on excision. Materials and methods: This comparative study was conducted in the Department of Pathology, University Medical and Dental College, Faisalabad from September 2008 to December 2011. All women who had a clinically palpable breast lump were subjected to fine needle aspiration cytology (FNAC) which was followed by an excision biopsy. Results: Fifty six patients who presented with a breast lump in the surgical and gynecological department at Madina Teaching Hospital were referred to the Pathology Department for FNAC. Thirty one were reported as C2 lesions, 1 was reported as C3, 1 as C4 and 23 cases were reported as C5 lesions. On histopathological examination, out of 31 cases which were reported as C2 lesions, 30 were benign while 1 case turned out to be medullary carcinoma of the breast (false negative). The case which was reported as C3 turned out to be a benign lesion-g...
IJPA, 2011
Introduction Breast cancer is the second most common cancer in women. FNAC is simple, rapid and safe method to diagnose breast lumps. FNAC has high sensitivity, specificity and accuracy.Objectives The aim of study was to correlate the FNAC diagnosis with histopathology and to find out the pattern of breast lump, sensitivity and specificity of FNAC in diagnosis of breast lumps in our institution. Method The present study was done in department of Pathology of Sri Venkateshwara Medical college Hospital and research Centre, Pondicherry, India from June 2008 to May 2010. The FNAC was done in 102 cases and histopathology was available in 77 (75.49%) cases for correlation with cytology.ResultsThe result shows 3.92% cases were male while 96.08% female. Age of the patient was range from 16-52 years with mean age of 30 years. In our study fibroadenoma was most common benign lesion in the breast which account 45.09% of the total breast lesion, and 89.1% seen in the age group of 10-30 yrs. Study includes 9(8.82%) cases of malignancy with mean age of 46 years. The sensitivity and specificity for malignancy were found to be 84.6% and100% respectively.ConclusionFNAC is highly sensitive and specific technique for diagnosis of most of the breast lumps. FNAC can be used preoperatively to avoid unnecessary surgery and discomfort during open biopsy.
Fine Needle Aspiration Cytology a Diagnostic Aid In Breast Lump In Ajims Mangalore
The study 'Fine Needle Aspiration Cytology A Diagnostic Aid In Breast Lump' was carried out in the department of general surgery of A J Institute of Medical Sciences and Research Centre, Mangalore over a period of two years from October 2016 to October 2018. The study group included 100 subjects who underwent FNAC. The study extensively proves that FNAC is certainly a diagnostic modality for patients presenting with breast lump. It demonstrates a high accuracy 97.4% and sensitivity of 96.8% with clinical diagnosis and histopathology.
Indian Journal of Applied-Basic Medical Sciences, 2021
INTRODUCTION: Breast cancer is the most common cancer in worldwide between age of 20-59 years females. It is responsible for 15% of total deaths due to cancers. FNAC is one of the important components of ‘triple approach’, which has been widely accepted for the preoperative diagnosis of breast lesions. AIM: To establish utility and effectiveness in diagnosis of breast lesion by FNAC and find the incidence of breast cancer in palpable lump in different age groups. MATERIAL AND METHODS: In this study100 cases of breast lump referred by the Surgery Department of LG Hospital was included in study period fromAugust2016toOctober2018. RESULT: Out of the 100 cases, in 99 cases the aspirates were adequate for interpretation. Out of 100, 90cases underwent a biopsy and could be correlated histopathologically. According to NHSBSP, there was 1 case in C1 category,64 cases in C2 category, 3 cases in C3 category, 2 cases in C4 category and 30casesin C5 category. CONCLUSION: The present ...
Comparison of the Diagnostic Accuracy of FNAC and Biopsy in the Diagnosis of a Palpable Breast Lump
Annals of International medical and Dental Research, 2018
Background: Mammary gland carcinoma is the most common malignant tumor. Annually worldwide more than1,000,000 cases of breast carcinoma occur, which is the leading cause of carcinoma death in women. The most relevant and important method to diagnose breast cancer is Fine Needle Aspiration Cytology (FNAC). The use of core needle biopsy (CNB) has been increasing because of various limitations. Advantages of core needle biopsy over FNAC is, that core needle biopsy provide sufficient tissue for definitive histological diagnosis, differentiate between invasive cancer and carcinoma. The purpose of this study was to determine if there is a difference in diagnostic accuracy in using CNB and FNAC in patients with palpable breast lumps undergoing breast surgery. Methods: This was cross sectional type of study conducted in the Department of General Surgery at Muzaffarnagar Medical College, Muzaffarnagar. The study was carried out from July 2016 to March 2018. The study population was recruited from the patients presenting with suspicious palpable breast lump clinically and/or radiologically, attending at General Surgery Outpatient Department (OPD), Muzaffarnagar Medical College, Muzaffarnagar. Hundred (100) patients suffering from breast lumps were included in this study. Results: Total 58 patients (58% of total patients with breast lump) were found with malignancy having C5 category of FNAC. All of them confirmed malignancy after the surgery. FNAC showed malignancy in 58% cases of breast lump. There was no false positive case in FNAC findings. Rest of 42 patients showed non-malignant breast lumps which showed C2, C3 and C4 category of FNAC. Findings after excision biopsy showed that there were 26 patients (26%) were false negative. Conclusion: Findings of the present study suggest that FNAC is almost equally effective technique for the diagnosis of malignancy in patients suffering carcinoma of mammies. FNAC is considered as an economical, less complicated, rapid and reliable method for the pathological diagnosis of breast carcinoma in a developing country like India. Malignant tumour can be exactly diagnosed by FNAC as it is highly sensitive for malignancy. CNB should be put after FNAC If initial FNAC fails to determine the type of tumour, CNB can be a useful second line method of pathological diagnosis in order to minimize the chance of missed diagnosis of breast cancer. Excision biopsy should be considered as last option for pathological diagnosis.
Diagnostic performance of fine needle aspiration cytology (FNAC) in the diagnosis of breast lumps
PubMed, 2013
Objective: The aim of the study was to evaluate the diagnostic performance of line needle aspiration cytology in the diagnosis of breast lumps. Methods: All patients who underwent FNA breast lumps at Rehman Medical Institute, Peshawar during 2006 to 2008 were included in this descriptive cross-sectional study. The FNA procedure was performed & interpreted by experienced cyto-pathologists. FNAC of 102 breast lumps were analysed. Results: The age range of the patients was 15-80 years (mean 38.11 years). Inadequate cases were 2.94%, malignant 30.39%, atypical/suspicious of malignancy 6.86%, and benign 59.80%. Malignant lesions predominated in the 5th and 6th and benign in the 3rd and 4th decades of life. Conclusion: FNAC of breast is simple, cost-effective and less traumatic method for diagnosis of breast lumps. Combined with physical examination and imaging studies, it is a highly sensitive diagnostic tool and can reduce the need for open biopsy.
Efficacy of FNAC in Diagnosis of Breast Lumps -A Retrospective Study
https://www.ijrrjournal.com/IJRR\_Vol.8\_Issue.9\_Sep2021/IJRR-Abstract03.html, 2021
Background: FNAC is an established and highly accurate method for diagnosis of breast lesions. Its further advantage is to give rapid diagnosis, cost-effectiveness, excellent patient acceptance and minimal or no morbidity. The study aimed to diagnose various breast masses before operation by FNAC and to compare the result of FNAC with histopathological study to assess the efficacy of FNAC. Materials and Methods: The study entitled "Efficacy of FNAC in diagnosis of Breast Lumps" is a retrospective study conducted in department of surgery with collaboration of pathology department at Nalanda Medical College and Hospital, Patna during the period of July 2017 to December 2019. During this period, 150 FNAC cases were selected for study. Results: Fibroadenoma was the most commonly diagnosed entity in benign breast lesions, followed by fibrocystic disease. Among malignant lesions, infiltrating ductal carcinoma was the most common. The overall diagnostic accuracy of FNAC in benign breast lesions was 94.59%. The fibroadenomas were correctly diagnosed in 92.96% cases. There were 5.41% false negative results in our series. There was no false positive result giving specificity of 100%. Conclusion: FNAC is an inexpensive, simple, safe and readily acceptable procedure to the patient and plays main role to provide rapid and accurate diagnosis of breast lumps. FNAC enables us to differentiate benign from malignant lesions with high sensitivity, specificity and diagnostic accuracy.
Classification of breast lumps on the basis of fine needle aspiration cytology or FNAC
IP innovative publication pvt. ltd, 2019
Introduction: FNAC is an essential part of the triple assessment method of preoperative evaluation of breast lumps or masses. So the aim of our present study is evaluation of the accuracy and effectiveness of FNAC for classification of breast lumps in our institute.. Specific inclusion and exclusion criteria were used in order to select the cases for the present study. Necessary and relevant data was statistically evaluated in terms of sensitivity, specificity, PPV, NPV, FPR, FNR and overall diagnostic accuracy. Kappa statistics and Chi-square tests were applied for further statistical significance. Results: Out of 215 cases of breast lumps that underwent FNAC, a total number of 145 cases were evaluated and classified into five categories from unsatisfactory (C1) to Malignant (C5). Sensitivity, specificity, PPV, NPV, FPR, FNR and overall diagnostic accuracy were 90.90%, 98.68%, 1.37%, 9.09%, 96.77%, 96.15% & 96.33% respectively. Conclusion: On the basis of FNAC reports, we can classify breast lesions into various categories from C1 to C5 and these cytological categories show a statistically significant correlation with final diagnoses given in subsequent histopathology reports.
Accuracy of fine needle aspiration cytology in categorization of breast lumps
IP Innovative Publication Pvt. Ltd., 2017
Diagnostic breast lump FNAC is an important part of of triple assessment. At a tertiary hospital retrospective study was done.The study compared malignant lesions diagnosed on fnac with its histopathological diagnosis. 125 cases were selected for the study of which 29 cases found to be positive for malignancy. Two cases found to be false negative. The sensitivity of FNAC for detection of malignancy was 92.59% while specificity 100%. The conclusion is that FNAC can be a very important diagnostic test in detecting malignancy in palpable breast lumps.The research show the final histopathology diagnosis highly correlating with the cytological diagnosis.