Antimicrobial and Mycochemical Analysis of Crude Extracts of Marine and Terrestrial Fungi (original) (raw)

2019, International Journal of Advanced Scientific Research and Management

In search of new bioactive compounds against human pathogens, marine and terrestrial fungi were isolated from Puducherry coastline and Bengaluru respectively. A comparative study was done on both terrestrial and marine fungi with respect to the mycochemical analysis and antimicrobial activity against Staphylococcus aureus, Salmonella typhi, Bacillus cereus, Escherichia coli and Candida albicans. Morphologically identified selected fungi were cultured for the production of secondary metabolites in Potato Dextrose Broth medium to obtain the crude extract using ethyl acetate. Mycoconstituents revealed the presence of tannins, terpenoids, steroids, phenolics and flavanoids in marine derived fungi SW13, in SW7 only phenolics and tanins were present. Terrestial fungi SS3 showed the presence of phenolics, tanins, flavanoids whereas SS7 showed the absence of all myco-constituents. The marine derived fungi SW13 gave effective inhibition to all the tested pathogens, whereas SW7 gave effective inhibition against S. typhi, B. cereus and C. albicans. While, terrestrial fungi SS3 recorded inhibition against S. aureus, S. typhi and B. cereus. SS7 showed no antimicrobial activity against pathogens.