A direct and sensitive electrochemical sensing platform based on ionic liquid functionalized graphene nanoplatelets for the detection of bisphenol A (original) (raw)
Microchemical Journal, 2019
BSA templated Au-Cu bimetallic nanoclusters (Au-Cu@BSA) were synthesized. The characteristics of the prepared bimetallic nanoclusters were demonstrated by UV-Vis absorption, fluorescence spectrometry and transmission electron microscopy. The Au-Cu@BSA was mixed by graphene nanoribbons (GNRs) and Au-Cu@BSA-GNRs was applied as a modifier of glassy carbon electrode (GCE). Also, the properties of the prepared sensors were investigated by cyclic voltammetry, square wave anodic stripping voltammetry and electrochemical impedance spectroscopy. Au-Cu@BSA-GNRs/GCE was employed for the low cost, high efficiency, rapid, selective and sensitive determination of bisphenol A (BPA) as an effective sensing layer of the electrochemical sensor. Upon the optimization of chemical and instrumental parameters, including pH, deposition potential and time, the oxidation peak current was linearly dependent on the concentration of BPA. The dynamic ranges of BPA were linear between 0.01 to 2.0 and 2.0 to 70 µmol L-1 , with a limit of detection 0.004 µmol L-1. The Au-Cu@BSA-GNRs/GCE has high selectivity, stability, repeatability, and reproducibility. These results suggest that the constructed sensor has an excellent capacity as an alternative to routine analysis methods for the determination of BPA. The constructed electrode was used for electrochemical determination of BPA in tap water, bottled water, baby bottle and food storage container by the standard addition method. The obtained results indicate the ability of the proposed method to detect BPA in different real sample matrices.
Analytical Chemistry, 2020
Bisphenol A, an endocrine disrupting compound, is widely used in food and beverage packaging, and it then leaches in food and source water cycles, and thus must be monitored. Here, we report a simple, low-cost and sensitive electrochemical sensor using graphene oxide and 20 1 functionalized multi-walled carbon nanotubes for the detection of BPA in water. This sensor electrode system combines the high surface area of graphene oxide and carbon nanotubes, and the superior host-guest interaction capability of 20 1 A diffusion-controlled oxidation reaction involving equal numbers of protons and electrons facilitated the electrochemical sensing of BPA. The sensor showed a twostep linear response from 0.05-5 µM and 5-30 : with a limit of detection of 6 nM. The sensors also exhibited a reproducible and stable response over one month with negligible interference from common inorganic and organic species, and an excellent recovery with real water samples. The proposed electrochemical sensor can be promising for the development of simple low-cost water quality monitoring system for monitoring of BPA in water.
Electrochemical Detection of Bisphenol A Using Graphene-Modified Glassy Carbon Electrode
2012
Graphene's nano-dimensional nature and excellent electron transfer properties underlie its electrocatalytic behavior towards certain substances. In this light, we have used graphene in the electrochemical detection of bisphenol A. Graphene sheets were produced via soft chemistry route involving graphite oxidation and chemical reduction. X-ray diffraction, Fourier transform infra-red (FT-IR) and Raman spectroscopy were used for the characterization of the as-synthesized graphene. Graphene exhibited amorphous structure in comparison with pristine graphite from XRD spectra. FTIR showed that graphene exhibits OH and COOH groups due to incomplete reduction. Raman spectroscopy revealed that multi-layered graphene was produced due to low intensity of the 2D-peak. Glassy carbon electrode was modified with graphene by a simple drop and dry method. Cyclic voltammetry was used to study the electrochemical properties of the prepared graphene-modified glassy carbon electrode using potassium ...
Sensing and Bio-Sensing Research, 2015
The synthesis of room-temperature stable ionic liquids was obtained via metathesis reaction, which was accomplished by the reaction 1,10-Phenanthroline monohydrate hydrochloride with lithium-bis(trifluoromethane)sulfonamide in water (shortly, 1,10-PhenanNTf 2 ). The prepared 1,10-PhenanNTf 2 was characterized in details with various conventional methods. Finally, it was mixed with conducting binders and deposited on flat-silver electrode (AgE) to result in a sensor that has a fast response to bisphenol A (BPA) in the phosphate buffer phase (PBP). Features include high sensitivity, low-sample volume, reliability, reproducibility, ease of integration, long-term stability, and enhanced electrochemical responses.
Nano-Structures & Nano-Objects, 2017
h i g h l i g h t s • FRET biosensor based on aptamer/functionalized graphene for ultrasensitive detection of bisphenol A. • Qualitative and quantitative detection of BPA were successfully elucidated and realized with limit of detection <1 pg/mL by assessing the change followed by recovery of fluorescent intensity on BPA addition. • We applied the developed sensor for real water (river water, drinking mineral water and tap water) samples because of its facile preparation and manipulation, scalability and excellent performance with good recovery. • The specificity is evaluated by measuring the fluorescent intensity change with BPA analogs (BP, BPB, BPC and DES) for benchmarking this biosensor.
Microchimica Acta, 2016
The main aim of the work was to develop an efficient strategy for preparing molecularly imprinted polymers (MIPs) on the surface of graphene oxide (GO) sheets. Amine functionalization of GO was accomplished by a facile and efficient procedure with 3-aminopropyltriethoxysilane (APTES). Then, the template was immobilized onto aminofunctionalized GO in order to improve the recognition ability of MIP-based sensors. Also, prior to polymerization, ethylene glycol dimethacrylate was grafted onto the APTES coated graphene oxide sheets by the Michael addition reaction. In this way, many homogeneous imprinting sites were formed on the GO sheets. The resulting composite was placed on a glassy carbon electrode (GCE) which then was used for determination of bisphenol A (BPA) by electrochemical technique. The composite of amino-functionalized GO and MIP (GO/ APTES-MIP) was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy and energy dispersive X-ray spectroscopy. The electrochemical behaviors of the sensors were investigated by cyclic voltammetry and differential pulse voltammetry (DPV) techniques. Compared with non-imprinted polymer, the DPV current response of MIP sensor is about 4.6 times larger. Under the optimized conditions, GO/APTES-MIP sensor displays two linear ranges (from 0.006 to 0.1 μM and 0.2 to 20 μM) for determination of BPA, and the detection limit is 0.003 μM (at an S/N ratio of 3). The MIP-based sensor was applied to the in-situ determination of BPA in milk and mineralised water without any pre-treatment and matrix interfering effects.
Polyaniline/carbon nanotube-graphite modified electrode sensor for detection of bisphenol A
Ionics, 2018
Endocrine disruptors bisphenol A (BPA) have dreadful impacts on both humans and animals. A highly sensitive polyaniline-MWCNT-graphite (PANI-MWCNT-Gr)-base electrode sensor has been developed for the detection of BPA in water. The nanocomposite electrode was fabricated using a facile sol-gel chemical route by the reaction of graphite electrode (Gr) and polyaniline/ multiwall carbon nanotube (PANI/MWCNT). Synergistic electrochemical interaction between MWCNT and PANI boosts electron transfer, resulting improvement in the generated current as compared to bare graphite and other reported electrodes. Consequently, a PANI/MWCNT-Gr-supported electrode sensor shows the unique potential of detecting BPA in a sub-nano range. Prepared nanocomposite electrode has been effectively employed for the detection of BPA in real samples (such as baby feed bottles), with more than 95% accuracy, which could potentially replace conventional detection systems. Advance experiments related to the stability of PANI/MWCNT-Gr-supported nanocomposite electrodes are in progress for replacing carbon electrodes in microbial fuel cells.
Journal of AOAC International, 2016
An electrochemical and sensitive sensing of 2,2-bis(4-hydroxyphenyl) propane [bisphenol A (BPA)] was developed based on a didodecyldimethylammonium bromide-modified expanded graphite paste electrode (DDAB-EGPE). The DDAB-EGPE was prepared by suspending an EGPE in a DDAB aqueous solution, and allowing the DDAB to form a hydrophobic film on the expanded graphite surface. Compared with the EGPE, the DDAB-EGPE showed improved electrochemical response of BPA because of the preconcentration of BPA in DDAB via hydrophobic interaction. Due to the electrocatalytic activity of BPA, a sensor for BPA was constructed based on the DDAB-EGPE. The DDAB-EGPE exhibited a wide linear response to BPA ranging from 6.0 × 10(-8) to 2.0 × 10(-5) mol/L with a detection limit of 7.1 nmol/L at S/N = 3. The designed sensor showed good reproducibility and stability. The proposed sensor was successfully applied to the determination of BPA in three types of real plastic product samples. This sensor presented a si...
Development of an electrochemical sensor of endocrine disruptor bisphenol A by reduced graphene oxide for incorporation of spherical carbon nanoparticles, 2019
This work describes the synthesis of graphene oxide (GO) and its reduction using only carbon nanoparticles with no conventional chemical reducer or external energy. The reduced graphene oxide formed through the incorporation of the carbon nanoparticles (rGO-CNPS) was characterized by HR-TEM techniques, UV–vis, Raman spectroscopy and electrochemical techniques. The rGO-CNPS nanomaterial was incorporated on the surface of the printed carbon electrode and used to determine the endocrine interferent bisphenol A. The SPE-rGO-CNPS electrode presented excellent response for bisphenol A at concentrations varying from 7.5×10−9 to 2.6×10−7 mol L−1 in PBS, pH 7 with sensitivity 189.5 μmol L−1 and detection limit of 1×10−9 mol L−1. The electrode also presented excellent performance even in the presence of the main phenolic interferences and was used for determination of bisphenol A in plastic-bottled drinking water.
An Exfoliated Graphite-Based Bisphenol A Electrochemical Sensor
2012
The use of an exfoliated graphite (EG) electrode in the square wave voltammetric detection of bisphenol A (a model phenolic pollutant) in water, whereby the phenolic electrode fouling challenge is mitigated, is described. The oxidation peak of BPA was observed at about 0.45 V in phosphate buffer solution at pH 10. The current response exhibited a linear relationship with the concentration over a range from 1.56 µM-50 µM. The detection limit was calculated to be 0.76 µM. The EG electrode surface was renewed after each measurement with excellent reproducibility. A real sample application was also investigated.
2020
A simple and rapid electrochemical sensor based on modified graphite nanoparticle with phosphotungstic acid and Nafion (GN–PTA–nafion) on glassy carbon electrode (GCE) has been developed for detecting bisphenol A (BPA). The GN was characterized using a scanning electron microscope (SEM) and X-ray diffractometer (XRD), while the modified GCE was characterized using differential pulse voltammetry (DPV) and cyclic voltammetry (CV). Several parameters such as GN concentration, scan rate, equilibrium time, and pH of phosphate buffer were optimized in this study. The GN–PTA–Nafion modified GCE that consists of graphite nanoparticle with a large surface area showed better and faster electron transfer, whereas the phosphotungstic acid (PTA) increased the sensitivity of the electrode for BPA detection. Good electrochemical performances for analyzing BPA, with a detection limit of 0.3995 mol L, as well as good reproducibility (RSD 2.51%) were obtained. The modified electrode showed that it ha...
Recent Advances in Electrochemical Sensors and Biosensors for Detecting Bisphenol A
Sensors, 2020
In recent years, several studies have focused on environmental pollutants. Bisphenol A (BPA) is one prominent industrial raw material, and its extensive utilization and release into the environment constitute an environmental hazard. BPA is considered as to be an endocrine disruptor which mimics hormones, and has a direct relationship to the development and growth of animal and human reproductive systems. Moreover, intensive exposure to the compound is related to prostate and breast cancer, infertility, obesity, and diabetes. Hence, accurate and reliable determination techniques are crucial for preventing human exposure to BPA. Experts in the field have published general electrochemical procedures for detecting BPA. The present timely review critically evaluates diverse chemically modified electrodes using various substances that have been reported in numerous studies in the recent decade for use in electrochemical sensors and biosensors to detect BPA. Additionally, the essential co...
Journal of the Brazilian Chemical Society
This paper describes a new and simple electrode for the determination of bisphenol A (BPA) in different plastic samples using carbon paste electrode (CPE) modified with a trihexyltetradecylphosphonium tetrachloromanganate(II) ([P 6,6,6,14 + ] 2 [MnCl 4 2− ]) magnetic ionic liquid (MIL/CPE). Electrochemical characterization of MIL/CPE by cyclic voltammetry and electrochemical impedance spectroscopy indicated that MIL facilitated the electron transfer. Using squarewave voltammetry (SWV) under optimized conditions, the calibration curve showed a linear range for BPA from 2.0 to 53.0 μmol L-1 , with limit of detection (LOD) of 0.87 μmol L-1. The proposed electrode demonstrated good precision with coefficients of variation of 4.5% (intra-day, n = 10), 2.0% (inter-day, n = 5) and 1.5% (electrode-to-electrode repeatability, n = 3). Recoveries of 93.0 to 101.1% demonstrated that the method is suitable for practical applications.
Food Analytical Methods, 2016
Rapid analysis of health hazardous materials is necessary to prevent foodborne illness in food control science. Bisphenol A (BPA) is one of the potentially hazardous materials that may potentially create adverse health effects, if its concentration level in food is not controlled. In this work, carbon paste electrode has been modified with CdO nanoparticles and ionic liquid (IL/CdO/CPE) for determination of BPA in food samples. In addition, vitamin B 6 (B6) has separated oxidation peak at modified electrode and simultaneous determination of BPA and B6 is possible. The square wave voltammetric peak currents of BPA and B6 at IL/CdO/CPE have linear relation to their concentrations in the range of 0.01 to 800 μmol L −1 BPA and 0.4 to 500 μmol L −1 B6. Selectivity of the modified electrode was studied, and it was successfully applied for analysis of food samples.
Journal of Analytical Methods in Chemistry, 2020
In the present work, we reported the simple way to fabricate an electrochemical sensing platform to detect Bisphenol A (BPA) using galvanostatic deposition of Au on a glassy carbon electrode covered by cetyltrimethylammonium bromide (CTAB). This material (CTAB) enhances the sensitivity of electrochemical sensors with respect to the detection of BPA. The electrochemical response of the modified GCE to BPA was investigated by cyclic voltammetry and differential pulse voltammetry. The results displayed a low detection limit (22 nm) and a linear range from 0.025 to 10 µm along side with high reproducibility (RSD = 4.9% for seven independent sensors). Importantly, the prepared sensors were selective enough against interferences with other pollutants in the same electrochemical window. Notably, the presented sensors have already proven their ability in detecting BPA in real plastic water drinking bottle samples with high accuracy (recovery range = 96.60%–102.82%) and it is in good agreeme...
MRS Proceedings, 2011
ABSTRACTThe advanced electrodes for detecting organophosphate pesticides were prepared by modification of the gold (Au) electrode with the reduced graphene oxide/ionic liquid (RGO/IL) nanohybrids. Due to the cationic and anionic parts, the ILs on RGO sheets provide the amount of functional groups for dispersion of hybrids and immobilization of organophosphorus hydrolase (OPH) enzymes. After the immobilization of OPH on the RGO/IL-modified Au electrodes, the modified electrodes represent faster electron transfer than that of Au electrode, resulting in high performance of biosensor with response time (~ 10 s) and sensitivity (4.56 nA μM−1). In addition, the OPH/RGO/IL-modified Au electrode displayed good stability and reproducibility.