Dynamin-Related Protein 1–Mediated Mitochondrial Mitotic Fission Permits Hyperproliferation of Vascular Smooth Muscle Cells and Offers a Novel Therapeutic Target in Pulmonary Hypertension
Feng Fu
Circulation Research, 2012
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The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases
Pierce Colpman
Cells, 2023
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Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension
Patricia Lima
Frontiers in physiology, 2018
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Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension
Monica Neuber-Hess
Journal of molecular medicine (Berlin, Germany), 2017
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Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension
Pierce Colpman
bioRxiv (Cold Spring Harbor Laboratory), 2023
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A novel fission-independent role of dynamin-related protein 1 in cardiac mitochondrial respiration
Shey-shing Sheu
Cardiovascular research, 2016
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Role of Dynamin-Related Protein 1 (Drp1)-Mediated Mitochondrial Fission in Oxygen Sensing and Constriction of the Ductus Arteriosus
Kalyani Trivedi
Circulation Research, 2013
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miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway
Bellur Prabhakar
PLoS Genetics, 2010
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Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer
Hugo Verdejo
The FASEB Journal, 2012
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MiD49 and MiD51: New mediators of mitochondrial fission and novel targets for cardioprotection
Izzah Ismail
Conditioning medicine, 2018
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Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation
Sestina Falcone
Cell Death & Differentiation, 2010
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An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications
Yolanda Madarnas
The FASEB Journal, 2020
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An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications
Yolanda Madarnas
The FASEB Journal, 2020
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Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension
Danchen Wu
Frontiers in Cell and Developmental Biology, 2023
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Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway
Jia Qi
Frontiers in pharmacology, 2018
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Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity
Ramesh Kandimalla
Human Molecular Genetics
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Translational Advances in the Field of Pulmonary Hypertension.From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics. Targeting Cell Growth and Proliferation Signaling Hubs
Soni Pullamsetti
American Journal of Respiratory and Critical Care Medicine, 2017
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Cdk1, PKCδ and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death
Scott Canfield
Biochemical and biophysical research communications, 2014
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Dynamin-Related Protein 1 at the Crossroads of Cancer
Miguel Melo
Genes, 2018
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Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability
Olga Ilkayeva
Molecular Biology of the Cell, 2011
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Correction: miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway
YANRUI LI
PLoS Genetics, 2010
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Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission
Laura Osellame
The Journal of Cell Biology, 2014
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Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury
Monica Neuber-Hess, Elahe Alizadeh, Stephen Archer, Danchen Wu
The FASEB Journal, 2019
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Physiological and Pathological Significance of Dynamin-Related Protein 1 (Drp1)-Dependent Mitochondrial Fission in the Nervous System
Shin Takasawa
Experimental Neurobiology, 2013
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Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities
Monica Neuber-Hess
Frontiers in Cardiovascular Medicine, 2019
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Alterations in c-Myc phenotypes resulting from dynamin-related protein 1 (Drp1)-mediated mitochondrial fission
Edward Prochownik
Cell Death & Disease, 2013
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Adaptor Proteins MiD49 and MiD51 Can Act Independently of Mff and Fis1 in Drp1 Recruitment and Are Specific for Mitochondrial Fission
Laura Osellame
Journal of Biological Chemistry, 2013
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Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury
Sang-Bing Ong, S. Subrayan
2010
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miR-138 and miR-25 Downregulate MCU, Causing Pulmonary Arterial Hypertension's Cancer Phenotype
Danchen Wu
American journal of respiratory and critical care medicine, 2016
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Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation
Rosemarie Mellado
Frontiers in Cell and Developmental Biology, 2014
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Fine-tuned repression of Drp1 driven mitochondrial fission primes a 'stem/progenitor-like state' to support neoplastic transformation
Brian Spurlock
eLife, 2021
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Mitochondrial dynamics in cardiovascular health and disease
Sang-Bing Ong
Antioxidants & Redox Signaling, 2013
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Mitochondrial Dysfunction in Pulmonary Hypertension
Ratoe Suraya
Antioxidants
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