Weak p53 permits senescence during cell cycle arrest (original) (raw)
Andrei Gudkov2010, Cell Cycle
visibility
…
description
6 pages
link
1 file
Related papers
P53 Isoforms Δ133P53 and P53Β Are Endogenous Regulators of Replicative Cellular Senescence
Nature Cell Biology, 2009
Repair or perish – the role of p53 protein in a cell’s life
Nowotwory. Journal of Oncology, 2019
Aging Cell, 2013
EXPRESSION OF p53 IN HUMAN BREAST CANCER
Biological Markers in Fundamental and Clinical Medicine (collection of abstracts), 2017
P53 at the Crossroads Between Cancer and Neurodegeneration
Free Radical Biology and Medicine, 2012
2019
p53 Gene Replacement for Cancer&Interactions with DNA Damaging Agents
Acta Oncologica, 2001
F1000 - Post-publication peer review of the biomedical literature, 2007
P53-FAMILY Proteins and Their Regulators: Hubs and Spokes in Tumor Suppression
Cell Death & Differentiation, 2010
Stage-specific sensitivity to p53 restoration during lung cancer progression
Nature, 2010
Loading Preview
Sorry, preview is currently unavailable. You can download the paper by clicking the button above.
Related papers
P53 in Breast Cancer: Mutation and Countermeasures
Frontiers in Bioscience, 2007
Senescence; an endogenous anticancer mechanism
Frontiers in Bioscience, 2012
P53: A Molecular Marker for the Detection of Cancer
Expert Opinion on Medical Diagnostics, 2008
A role for p53 in DNA end rejoining by human cell extracts
Mutation Research/DNA Repair, 1997
On the shoulders of giants: p63, p73 and the rise of p53
Trends in Genetics, 2002
Early stages of p53-induced apoptosis are reversible
Cell Death & Differentiation, 2001
Mutations in p53, p53 protein overexpression and breast cancer survival
Carolina Digital Repository (University of North Carolina at Chapel Hill), 2009
Cloning and Characterization of a Cell Senescence Gene for Breast Cancer Cells
PLoS Genetics, 2011
Beyond initiation: Human P53 plays role in transcription elongation
2016
2023
p63 and p73, members of the p53 gene family, transactivate PKCδ
Biochemical Pharmacology, 2006
Experimental Cell Research, 1999
Complex analysis of the p53 tumor suppressor in lung carcinoma
Oncology Reports, 2015
Translational approaches targeting the p53 pathway for anti-cancer therapy
British Journal of Pharmacology, 2012
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
Pigment Cell & Melanoma Research, 2010
Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro
Oncogene, 1999
P53 is Essential for Chemotherapy-Induced Hair Loss
2000
P53 Nuclear Accumulation as an Early Indicator of Lethal Prostate Cancer
British Journal of Cancer, 2019
p53-Dependent Transcriptional Responses to Interleukin-3 Signaling
PloS one, 2012
Selective pericentromeric heterochromatin dismantling caused by TP53 activation during senescence
Nucleic Acids Research, 2022
Molecular Cell, 2010
DNA damage-induced cell-cycle phase regulation of p53 and p21waf1 in normal and ATM-defective cells
Oncogene, 2003
Molecules and Cells, 2011
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression
Oncogene, 2003
Related topics
SenescenceBiologyCell CycleCell BiologyDNA damageMedicineCell lineDoxorubicinImidazolesBiochemistry and cell biology