Gout in Paleopathology: A Review with Some Etiological Considerations (original) (raw)

Characterization of gout in a skeletal population sample: Presumptive diagnosis in a micronesian population

American Journal of Physical Anthropology, 1995

Characterization of the nature and skeletal distribution of gout was accomplished in a Chamoru (Chamorros) population with predilection to the disease. Uniform excavation by the gouty diathesis produces a punched-out appearance to these predominantly monarticular lesions. The lesion is distinct from that seen in rheumatoid arthritis, spondyloarthropathy, or infection. Reactive new bone formation in some gouty lesions also has an apparently unique, ivory-like discoloration (contrasted with the adjacent bone), which facilitates diagnosis.

A comprehensive review on gout: the epidemiological trends, pathophysiology, clinical presentation, diagnosis and treatment

Journal of the Pakistan Medical Association, 2020

This review is aimed at provision of an updated knowledge about the gout and highlights the various areas which need to be focused for better healthcare. Relevant published articles in English Language were reviewed by utilizing various available databases including: Google Scholar, Springer Link, Science Direct and MEDLINE. The data reveal a precipitating number of gout cases from the developed countries, while the developing countries on the other hand are faced with an even higher threat. The risk factors and pathophysiology of gout are immaculate and clearly established. Hence, appropriate measures can be explored and worked on to pinpoint diagnosis, effective and economical treatment. Continuous...

On the early uses of the word 'gout': novel evidence and a critical assessment of the published literature

Reumatismo

When Was the Word 'Gout' First Used? A new study traces the origin of the word to the 10th century, challenging long-held beliefs One of the earliest diseases to be documented, gout remains a major health issue with increasing prevalence and incidence. But when was the word "gout" first used? Scholars have widely believed that it was first coined by a monk named Randolphus of Bocking in the 13th century. Now new evidence suggests the word "gout" was first used as early as the 10th century in the biography of a martyred nun

Gout: an Asia-Pacific update

International journal of rheumatic diseases, 2017

Even though, Hippocrates recognized gout as an affection of older men and a product of high living long back in 5th century BC, this painful condition promises to accompany humanity to the 21st century. The incidence is progressively rising and females are also affected in the modern era. There are also regional and ethnic variations in the incidence, the genetics of which is being studied. The recommended best therapy for the acute attacks and long term prophylaxis has improved remarkably in the recent years. However, patients are often treated inadequately and risk factors for their disease are not well explored in daily practice. Although well designed long term studies of current and newer treatment are welcomed, educating doctors especially the primary care physicians who manage majority of gout cases, in optimizing the currently available management options would improve the present care.