Evaluation of the predictive value of total IgE and absolute eosinophil levels on allergy test positivity (original) (raw)
A topy is the genetic predisposition for the production of antibody immunoglobulin E (IgE) as a response to low-dose common environmental factors such as pollen, house dust mites, and food allergens. An atopic individual has a high probability of developing one or more of the diseases such as atopic dermatitis (AD), asthma and allergic rhinoconjunctivitis, and food allergies [1, 2]. Allergic march is used to express the natural course of atopic diseases. A baby born to atopic parents and carrying the genetic burden of atopy has the ability to respond and sensitize to allergens, it encounters from the 1 st days of its life. Usually, the first allergic disease to be seen is AD, followed by clinical findings of food allergy (FA). FA, which is present in most of the cases with AD, has an important role in the pathogenesis of the disease. In the later years of life, sensitivity to respiratory allergies develops, and bronchial asthma and allergic rhinitis (AR) findings are added to the table [3].