original ) (raw )Upregulation of Scavenger Receptor B1 Is Required for Steroidogenic and Nonsteroidogenic Cholesterol Metabolism in Prostate Cancer
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Cancer Research, 2019
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Knockdown of scavenger receptor Class B Type I reduces prostate specific antigen secretion and viability of prostate cancer cells
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The Prostate, 2011
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Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model
Jenn Locke
The Prostate, 2009
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Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover
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Cancer & Metabolism
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Cholesterol Triggers Nuclear Co-Association of Androgen Receptor, p160 Steroid Coactivators, and p300/CBP-Associated Factor Leading to Androgenic Axis Transactivation in Castration-Resistant Prostate Cancer
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Cellular Physiology and Biochemistry
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Cholesterol biosynthesis inhibitor RO 48-8071 suppresses growth of hormone-dependent and castration-resistant prostate cancer cells
Benford Mafuvadze
OncoTargets and therapy, 2016
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Androgen-Independent Prostate Cancer Cells Acquire the Complete Steroidogenic Potential of Synthesizing Testosterone From Cholesterol
shafiq khan
Molecular and cellular endocrinology, 2008
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SR-B1 uptake of HDL promotes prostate cancer proliferation and tumor progression
Emmanuel Opoku
2020
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Human prostate cancer cells lack feedback regulation of low-density lipoprotein receptor and its regulator, SREBP2
Millie Hughes-fulford
International Journal of Cancer, 2001
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SR-BI: Linking Cholesterol and Lipoprotein Metabolism with Breast and Prostate Cancer
Stephan Chevalier
Frontiers in Pharmacology, 2016
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The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes.
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Dysregulation of Sterol Response Element-Binding Proteins and Downstream Effectors in Prostate Cancer during Progression to Androgen Independence
Majid Akbari
2004
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The importance of LDL and cholesterol metabolism for prostate epithelial cell growth
Teemu Murtola
PloS one, 2012
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Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development
Michael Lisanti
Breast Cancer Research, 2013
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Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts
Jayoung Kim
Journal of Clinical Investigation, 2005
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Scavenger receptor class B, type I on non-malignant and malignant human epithelial cells mediates cholesteryl ester-uptake from high density lipoproteins
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The International Journal of Biochemistry & Cell Biology, 2003
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Cholesterol synthesis pathway genes in prostate cancer are transcriptionally downregulated when tissue confounding is minimized
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BMC Cancer
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Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function
Wenjun Shen
Journal of lipid research, 2018
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Cancer-associated fibroblasts promote prostate tumor growth and progression through upregulation of cholesterol and steroid biosynthesis
Karin Jöhrer
Cell Communication and Signaling
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Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat
Attilio Rigotti
Journal of Clinical …, 1996
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Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC)
Yanquan Zhang
Journal of Biological Chemistry
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The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
John Griffiths
The EMBO Journal, 2011
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Cholesterol Synthesis Pathway Genes in Prostate Cancer are consistently downregulated when tissue confounding is minimized
May-britt Tessem
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Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism
Aud Svindland
Oncotarget, 2015
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Intratumoral steroidogenesis in castration-resistant prostate cancer: a target for therapy
Inna Ar
2014
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Androgen deprivation therapy improves the in vitro capacity of high-density lipoprotein (HDL) to receive cholesterol and other lipids in patients with prostate carcinoma
Raul Maranhão
Lipids in Health and Disease, 2020
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Castration-resistant prostate cancer: Targeting androgen metabolic pathways in recurrent disease
Bruce Montgomery
Urologic Oncology: Seminars and Original Investigations, 2009
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Androgens, lipogenesis and prostate cancer
Guido Verhoeven
The Journal of Steroid Biochemistry and Molecular Biology, 2004
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