Complement Dysregulation and Disease: Insights from Contemporary Genetics (original) (raw)

Complement System Part I – Molecular Mechanisms of Activation and Regulation

nicolas MERLE

Frontiers in Immunology, 2015

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Defective Complement Inhibitory Function Predisposes to Renal Disease

Patty Atkinson

Annual Review of Medicine, 2013

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Disease-Causing Mutations in Genes of the Complement System

Søren Degn, Jens Jensenius

The American Journal of Human Genetics, 2011

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The significance of the complement system for the pathogenesis of age-related macular degeneration — current evidence and translation into clinical application

Victor Chong

Graefe's Archive for Clinical and Experimental Ophthalmology, 2010

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Complement 1 Inhibitor Is a Regulator of the Alternative Complement Pathway

Haobo Jiang

Journal of Experimental Medicine, 2001

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Rare Loss-of-Function Mutation in Complement Component C3 Provides Insight into Molecular and Pathophysiological Determinants of Complement Activity

John Lambris

Journal of immunology (Baltimore, Md. : 1950), 2015

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Glomerular Diseases Dependent on Complement Activation, Including Atypical Hemolytic Uremic Syndrome, Membranoproliferative Glomerulonephritis, and C3 Glomerulopathy: Core Curriculum 2015

Marina Noris

American journal of kidney diseases : the official journal of the National Kidney Foundation, 2015

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Age-related Macular Degeneration and Complement Activation–related Diseases

Ian Douglas

Ophthalmology, 2008

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A Novel Role of Complement in Retinal Degeneration

Minzhong Yu

Investigative Ophthalmology & Visual Science, 2012

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Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome

Ronny Decorte

Proceedings of the National Academy of Sciences, 2003

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Complement in disease: a defence system turning offensive

John Lambris

Nature Reviews Nephrology, 2016

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Complement in atherosclerosis: friend or foe?

Johann Wojta

Journal of Thrombosis and Haemostasis, 2011

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Complement Activation: The role in Health and Disease and Strategies of Therapeutic Complement Inhibition

Nurun Nahar Mawla

American Journal of Medical Sciences and Medicine, 2014

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Complement in age-related macular degeneration: a focus on function

anne hughes

Eye, 2011

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The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited

Ethan Lai

Progress in Retinal and Eye Research, 2010

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Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome

vincent durey

2008

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Diagnosis of complement alternative pathway disorders

Antonello Pani

Kidney international, 2016

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Complement System Part II: Role in Immunity

Remi Noe, nicolas MERLE

Frontiers in Immunology, 2015

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Human genetic deficiencies reveal the roles of complement in the inflammatory network: Lessons from nature

Ebbe Thorgersen, Morten Harboe

Proceedings of the National Academy of Sciences, 2009

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Complement in human diseases: Lessons from complement deficiencies

P. Macor

Molecular Immunology, 2009

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The control of the complement lectin pathway activation revisited: Both C1-inhibitor and antithrombin are likely physiological inhibitors, while α2-macroglobulin is not

Peter Zavodszky

Molecular Immunology, 2013

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Complement deficiency and disease: An update

Göran Jönsson

Molecular Immunology, 2006

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aHUS caused by complement dysregulation: new therapies on the horizon

Christoph Licht

Pediatric Nephrology, 2010

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