P186 Impact of tofacitinib maintenance therapy on key Ulcerative Colitis patient-reported outcomes of fatigue, urgency, abdominal pain and sexual dysfunction using IBDQ and SF-36 individual items as proxies (original) (raw)

Tofacitinib in Patients with Ulcerative Colitis: Inflammatory Bowel Disease Questionnaire Items in Phase 3 Randomized Controlled Induction Studies

Joseph Cappelleri

Inflammatory Bowel Diseases, 2020

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Health-Related Quality of Life Outcomes With Tofacitinib Treatment in Patients With Ulcerative Colitis in the Open-Label Extension Study, OCTAVE Open

Sean Gardiner

Inflammatory Bowel Diseases

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Improvements in Disease Activity Partially Mediate the Effect of Tofacitinib Treatment on Generic and Disease-Specific Health-Related Quality of Life in Patients with Ulcerative Colitis: Data from the OCTAVE Program

Joseph Cappelleri

Digestive Diseases

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Randomized trial of tofacitinib in active ulcerative colitis: analysis of efficacy based on patient-reported outcomes

Joseph Cappelleri

BMC Gastroenterology, 2015

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Direct and Indirect Effects of Tofacitinib on Treatment Satisfaction in Patients with Ulcerative Colitis

Joseph Cappelleri

Journal of Crohn's and Colitis, 2016

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Outcomes of Tofacitinib Dose Reduction in Patients with Ulcerative Colitis in Stable Remission from the Randomised RIVETING Trial

Sean Gardiner

2020

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Tofacitinib Response in Ulcerative Colitis (TOUR): Early Response After Initiation of Tofacitinib Therapy in a Real-world Setting

Bruce Salzberg MD, FACG

Inflammatory Bowel Diseases

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Characteristics, clinical outcomes and patient-reported outcomes of patients with ulcerative colitis receiving tofacitinib: a real-world survey in the United States and five European countries

Joseph Cappelleri

BMC Gastroenterology, 2023

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Tofacitinib, an oral Janus kinase inhibitor, in active ulcerative colitis

William Sandborn

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Effectiveness and Safety of Tofacitinib in the Management of Ulcerative Colitis: A Brazilian Observational Multicentric Study

Fábio V. Teixeira

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P334 Impact of disease duration on tofacitinib efficacy in patients with ulcerative colitis

ES Maller

Journal of Crohn's and Colitis, 2020

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Assessment of Safety and Efficacy of Tofacitinib, Stratified by Age, in Patients from the Ulcerative Colitis Clinical Program

Gosford Sawyerr

Inflammatory Bowel Diseases

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P286 Sustained improvement in health-related quality of life outcomes in patients with Ulcerative Colitis with long-term tofacitinib treatment in the open-label extension study, OCTAVE Open

Sean Gardiner

Journal of Crohn's and Colitis, 2022

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Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis

Dahong Yu

The New England journal of medicine, 2017

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Real-Life Efficacy of Tofacitinib in Various Situations in Ulcerative Colitis: A Retrospective Worldwide Multicenter Collaborative Study

Csilla Keresztes

Inflammatory Bowel Diseases

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Extraintestinal manifestations at baseline, and the effect of tofacitinib, in patients with moderate to severe ulcerative colitis

ES Maller

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Efficacy and Safety of Tofacitinib for Treatment of Moderate to Severe Active Ulcerative Colitis: First Report from Iran

Homayoon Vahedi

Archives of Iranian medicine, 2021

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Efficacy and safety of tofacitinib dose de-escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open

ES Maller

Alimentary Pharmacology & Therapeutics

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Disease Activity and Health-related Quality of Life Relationships with Work Productivity in Patients with Ulcerative Colitis in OCTAVE Induction 1 and 2 and OCTAVE Sustain

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A Phase 2 Study of Tofacitinib, an Oral Janus Kinase Inhibitor, in Patients With Crohn’s Disease

Glenn L Gordon MD

Clinical Gastroenterology and Hepatology, 2014

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Tofacitinib for induction and maintenance therapy of Crohn's disease: results of two phase IIb randomised placebo-controlled trials

ES Maller

Gut, 2017

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Tofacitinib for the treatment of moderately to severely active ulcerative colitis: a systematic review, network meta-analysis and economic evaluation

Natalie Bohm

BMJ Open Gastroenterology

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Long-term safety and tolerability of oral tofacitinib in patients with Crohn’s disease: results from a phase 2, open-label, 48-week extension study

ES Maller

Alimentary Pharmacology & Therapeutics, 2019

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Disease Burden and Patient-Reported Outcomes Among Ulcerative Colitis Patients According to Therapy at Enrollment Into CorEvitas’ Inflammatory Bowel Disease Registry

Vipin Arora

Crohn's & Colitis 360, 2022

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The Inflammatory Bowel Disease Questionnaire in Randomized Controlled Trials of Treatment for Ulcerative Colitis: Systematic Review and Meta-Analysis

Martha Bayliss

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P781 Treatment outcome of tofacitinib dose reduction to 5 mg BID vs remaining on 10 mg BID in patients with Ulcerative Colitis who were in stable remission on 10 mg BID: Updated 30-month data from the double-blind, randomised RIVETING study

Sean Gardiner

Journal of Crohn's and Colitis, 2023

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P571 Vedolizumab (VDZ) real-world outcomes in ulcerative colitis (UC)

Jakob Begun

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P550 Characterisation of hospitalised patients with ulcerative colitis treated with tofacitinib in the OCTAVE clinical programme for up to 7.8 years

Sean Gardiner

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Ulcerative Colitis-Symptom Questionnaire: Valid for Use in Adults with Moderately to Severely Active Ulcerative Colitis

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Psychometric validation of the SF-36® Health Survey in ulcerative colitis: results from a systematic literature review

Martha Bayliss

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Tofacitinib Treatment is Associated with Modest and Reversible Increases in Serum Lipids in Patients with Ulcerative Colitis

Pam Taub

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Delayed and limited administration of the JAKinib tofacitinib mitigates chronic DSS-induced colitis

Friederike Berberich-siebelt

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Effects of tofacitinib monotherapy on patient-reported outcomes in a randomized phase 3 study of patients with active rheumatoid arthritis and inadequate responses to DMARDs

Joel Kremer

Arthritis Research & Therapy, 2015

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Longitudinal monitoring of STAT3 phosphorylation and histologic outcome of tofacitinib therapy in patients with ulcerative colitis

Valery Volk

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Further Validation of the Crohn’s and Ulcerative Colitis Ques-tionnaire-32 (CUCQ-32) to Measure the Quality of Life in Pa-tients Treated with Biologics Therapy

Professor Laith Al-Rubaiy PhD, FRCP

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