Biofilms: A Survival and Resistance Mechanism of Microorganisms (original) (raw)

Biofilms are complex communities of microorganisms that exhibit remarkable resistance to environmental challenges and antimicrobial treatments. These structures are formed through distinct developmental stages, including adhesion, extracellular matrix synthesis, maturation, and dispersion, which enhance the survival of microorganisms in hostile environments. The presence of biofilms is associated with various infections that pose significant treatment challenges due to their intrinsic resistance mechanisms. Future therapy strategies must focus on developing methods to disrupt biofilm formation and enhance the efficacy of antibiotics.