Trends and outcomes of sepsis hospitalizations complicated by acute kidney injury requiring hemodialysis (original) (raw)

2017, Journal of Critical Care

AI-generated Abstract

Sepsis is a significant cause of mortality in the U.S., often complicated by acute kidney injury (AKI), especially in severe cases requiring dialysis (AKI-D). An analysis of the National Inpatient Sample from 2002 to 2013 revealed that AKI-D occurred in 2.64% of septicemia hospitalizations, with an alarming increase over the years. Patients with AKI-D were generally younger, male, and had a higher prevalence of comorbidities, leading to double the mortality rate compared to those without AKI-D. Despite the apparent increase in risk, factors like shifting demographics and comorbidities explained the trend, indicating a complex relationship between AKI-D and sepsis outcomes.

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