Architecture of a pulmonary thrombus removed during embolectomy in a patient with acute pulmonary embolism (original) (raw)

2010, The Journal of Thoracic and Cardiovascular Surgery

AI-generated Abstract

This research investigates the architecture of a pulmonary thrombus removed during embolectomy in a patient with acute pulmonary embolism, analyzed using scanning electron microscopy (SEM). Findings indicate that the thrombus is composed of tightly packed, thick fibrin fibers with a distinct lack of layered structure, contrasting with thrombi from coronary artery patients. The study suggests that the unique fibrin arrangement might contribute to the resistance of pulmonary thrombi to endogenous fibrinolysis, enhancing understanding of treatment limitations in large pulmonary emboli.

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