Metanalysis of Heterotopic Ossification (HO) Following Cervical Artificial Disc Replacement (CADR) (original) (raw)

Meta-analysis was conducted to investigate heterotopic ossification (HO) incidence following cervical artificial disc replacement (CADR). Findings show that HO incidence is influenced by implant type, data class, and follow-up duration. Class I data indicated an overall incidence of HO for ProDisc-C at 8%, Kineflex-C at 4%, and Prestige with zero incidence, while Class II data presented significantly higher HO rates for ProDisc-C (71-88%) and Mobi-C (52-75%). There were no strong indications that pharmacological means effectively prevent HO, though surgical additions like an anterior phalange showed promise.