Restless Legs Syndrome in Copd Patients Without Accompanying Disease (original) (raw)
Depression and Sleep Quality in Patients with Restless Legs Syndrome
Journal of Turkish Sleep Medicine
Objective: Restless Legs Syndrome (RLS) is a common neurological disorder that affects patients' sleep, emotional state and daily life negatively. In this study it was aimed to determine the sleep quality, daytime sleepiness and depression frequency in patients with RLS and their relation with duration and severity of illness. Materials and Methods: In our center, 41 patients with primary RLS diagnosis were included in the study. Patients were divided into groups as mild, moderate, severe and very severe, according to the RLS severity scale of the International Restless Legs Syndrome Study Group. Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, and Beck Depression Inventory were filled in by all the patients, including identity and sociodemographic data with illness information. Statistical analysis was performed among groups divided according to disease severity. Depressive symptoms of the disease duration and its relation with sleep problems were investigated. Results: In this study 41 patients, 30 (73.2%) female, 11 (26.8%) male, were included. Of the patients participating in the study, 2 patients (4.9%) had mild RLS while 7 (17.1%) were very severely ill. Fourteen patients (34.1%) had moderate disease and 18 (43.9%) had severe disease. Bad sleep quality was found in 68.3% (n=28) of patients with RLS, excessive daytime sleepiness in 14.6% (n=6) severe depression in 7.3% (n=3) and totally 29.3% of patients (n=12) depressive symptoms were observed. As the severity of illness increased, sleep quality deteriorated and depressive symptoms increased (p<0.01). Conclusion: Most of the RLS patients had poor sleep quality, a significant amount of daytime excessive sleepiness, and about one third of them had depression. As the duration and severity of the disease increases, the intensity of depressive symptoms increases. Remembering that RLS may have serious consequences and effective treatment of depression when accompanied should be planned without losing time.
The Relationship Between Restless Legs Syndrome and Cardiovascular Risk Factors
Journal of Turkish Sleep Medicine
Objective: Restless Legs syndrome (RLS) is one of the common sleep disorders in the community. There are many studies on the relationship between sleep disorders and diabetes, hypertension, hyperlipidemia, obesity, and metabolic dysregulation. However, the results are contradicting in the studies conducted in cases with RLS. In this study, we retrospectively examined the possible relationship between cardiovascular risk factors and RLS. Materials and Methods: The study included 107 patients (group 1) diagnosed with RLS according to the diagnostic criteria recommended by the international RLS study group and 97 patients with the diagnosis of simple snoring (group 2) among the patients who were prescribed a diagnosis of sleep disorder in the sleep laboratory. Demographic, laboratory and polysomnographic data of all cases were retrospectively reviewed. Results: There was no significant difference between the groups in terms of age, gender, smoking, and alcohol use, however, weight, neck circumference, waist circumference, and body mass index were detected significantly higher (p=0.008, p=0.020, p=0.001, p=0.002, respectively). In addition, diastolic and systolic arterial blood pressure values and total cholesterol, low density lipoprotein-cholesterol, and triglyceride levels measured at the night of the examination were significantly different between the groups, and the presence of Metabolic syndrome was observed significantly higher in the RLS group (p=0.001, p=0.001, p=0.024, p=0.033, p=0.020, p=0.002, respectively). Conclusion: The incidence of hypertension, hyperlipidemia, obesity, and Metabolic syndrome increases in RLS patients. Further prospective studies are needed to elucidate the potential mechanisms underlying this correlation between the RLS and cardiovascular risk factors.
Restless Legs Syndrome and Cognitive Functions
Journal of Turkish Sleep Medicine
Huzursuz Bacaklar sendromu (HBS), akşam saatlerinde başlayan özellikle alt ekstremitelerde belirgin hareket ettirme dürtüsünün eşlik ettiği ve hastanın uykuya dalmasını engelleyen sensori-motor karakterde, klinik pratikte sık karşılaşılan bir uyku bozukluğudur (1,2). Kadınlarda iki kat daha fazladır ve prevelansı yaş ile birlikte artmaktadır (3). HBS için yapılan prevalans çalışmalarında farklı toplumlarda farklı sonuçlar elde edilmiştir. Bu oran genel popülasyonda yaklaşık %5-15 arasındadır (4). Türkiye'de yapılan çeşitli çalışmalarda ise %3,19-22,2 arasında değişen oranlar bildirilmiştir (5-7). HBS ve bilişsel fonksiyonlar üzerindeki etkisi ile ilgili kısıtlı sayıda çalışma bulunmaktadır (8-11). Bazı çalışmalar özellikle Abstract Öz Objective: Restless Legs syndrome (RLS) is a common sleep disorder in clinical practice. In the prevalence studies conducted in different populations for RLS, different results ranging from 5% to 15% were obtained. This ratio ranges from 3.19% to 22.2% in Turkey. RLS, known to have adverse effects on sleep quality, can also affect mood, attention and cognitive functions. In our study, we aimed to investigate the possible effect of RLS on cognitive functions. Materials and Methods: In this study, patients diagnosed with RLS in the neurology outpatient clinic of our hospital were evaluated. Patients with possible mild cognitive impairment were excluded from the study by using the Standardized Mini Mental Test. After exclusion of secondary causes for RLS, 45 patients with idiopathic RLS and 20 healthy individuals were included in the study.
Restless Legs Syndrome in Adolescents with Functional Abdominal Pain
Pediatric Practice and Research, 2016
Çalışmamızda fonksiyonal karın ağrısı (FKA) olan adölesanlarda huzursuz bacak sendromu (HBS) sıklığını saptamayı amaçladık. Gereç yöntem: Kliniğimizde FKA tanısı ile takip edilen yaşları 12 ile 16 yıl arasında değişen 79 olgu ve benzer yaş ve cinsiyette toplam 92 sağlıklı adölesan kontrol grubu olarak alındı. Tüm olgularda HBS varlığı Uluslararası HBS Çalışma Grubunun belirlediği HBS tanısı için hazırlanmış tanı formu kullanılarak sorgulandı. Tanı formundaki 4 sorunun tümüne evet yanıtı veren hastalara kesin HBS tanısı konuldu Bulgular: FKA'lı 79 hastanın 16'sında (%20,.2) ve 92 sağlıklı kontrolün 4'ünde (%4,3) HBS saptandı. FKA'lı hastalarda HBS oranı kontrol grubuna göre istatistiksel olarak anlamlı oranda yüksekti (p<0,01). Sonuç: HBS prevalansı FKA'lı adölesanlarda sağlıklı kontrol grubuna göre daha fazla oranda saptandı .
The incidence of Restless leg syndrome in Pregnancy
Turkish Journal of Obstetrics and Gynecology, 2007
OBJECTIVE: We investigated to evaluate the incidence of Restless leg syndrome (RLS) in pregnants applied to our hospital. MATERIALS- METHODS: Four hundred pregnant women those applied to our University Obstetrics and Gynecology Clinic were taken to our study. A questionnaire including demographic features and RLS symptoms was interrogated. RESULTS: The mean age of the pregnants was 27.4±5.3 (17-55). The incidence of RLS in pregnancy was found 19%. There was not any significant difference between the trimesters of pregnancy for the incidence of RLS. Snoring, apnea, daytime fatigue were significantly higher in RLS pregnants. Day time sleepiness was higher in RLS pregnants but this was not statistically significant. DISCUSSION: RLS is a pathology that is not well known by doctors and patients especially pregnants. For this reason pregnants should be evaluated for RLS symptoms. Researches are needed considering the ethiopathogenesis of RLS, a situation destroying the life quality.
Evaluation of Sensory Nerve Conduction Studies and Hematologic Parameters in Restless Legs Syndrome
Turkish Journal Of Neurology, 2020
Amaç: Huzursuz bacaklar sendromu (HBS) bacaklarda yanma gibi duysal yakınmalar ile ortaya çıkan bir hastalıktır. Hastalar bacaklarını hareket ettirmek isterler. Semptomlar istirahatle ve geceleri belirginleşir. Bu çalışma ile HBS'de duysal sinir iletimlerinin hematolojik kan parametreleri ile ilişkisinin incelenmesi amaçlanmıştır. Gereç ve Yöntem: Çalışmaya 45 HBS'li hasta ve 45 sağlıklı kontrol dahil edildi. Hastaların yaş, cinsiyet ve kronik hastalıkları sorgulandı. Hemoglobin, ortalama korpusküler hacim (MCV), ortalama korpusküler hemoglobin (MCH), ortalama korpusküler hemoglobin konsantrasyonu (MCHC) ve ferritin değerleri kaydedildi. Ulnar, medyan ve sural duysal sinir amplitüd, latans ve iletim hızı elektronöromiyografi laboratuvarında değerlendirildi. Veriler SPSS 21 kullanılarak tanımlayıcı, parametrik ve nonparametrik testler ile analiz edildi. Bulgular: Çalışmada 22 (%49) kadın ve 23 (%51) erkek HBS'li hasta vardı. Yaş ortalaması 57,31±14,47 yıl idi. Hemoglobin (g/dl) 14,06±1,88; MCV (fl) 85,70 (55,7-96,5); MCH (pg) 28,45 (17,6-32,5) ve ferritin (ng/ml) 31,30 (4-848) seviyelerindeydi. HBS ve kontrol grubu arasında kan değerleri açısından fark saptanmadı (p>0,05). Sural sinir iletim hızı HBS'li hastalarda daha düşüktü (p=0,01). Sural sinir latansı daha uzundu (p=0,01). Diğer sinir iletimleri hasta ve kontrol grubunda benzerdi (p>0,05). Sonuç: HBS patogenezinde santral sinir sistemi dopaminerjik mekanizmaları, genetik geçiş ve düşük ferritin değerleri ön plandadır. Periferik sinir sistemi üzerinde daha az durulmaktadır. Bu çalışmada HBS hastalığı ile sural sinir iletim hızı ve latansı arasında ilişki olduğu belirlenmiştir. Ancak ferritin seviyesi ve sinir iletimleri arasında ilişki saptanmamıştır. Anahtar Kelimeler: Huzursuz bacaklar sendromu, duysal sinir, ferritin Objective: Restless legs syndrome (RLS) presents with sensory symptoms such as burning in the legs, patients want to move their legs. Symptoms become apparent at rest and at night. The aim of this study was to investigate the relationship between sensory nerve conduction and hematologic parameters in RLS. Materials and Methods: Forty-five patients with RLS and 45 healthy controls were included in the study. Age, sex, and chronic diseases of the patients were questioned. Hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and ferritin values were recorded. Ulnar, median, and sural sensory nerve amplitude, latency and conduction velocity were evaluated in a electroneuromyography laboratory. Data were analyzed using descriptive, parametric and nonparametric tests with the SPSS 21 software. Results: There were 22 (49%) female and 23 (51%) male patients with RLS in the study. The mean age was 57.31±14.47 years. Mean blood values were as follows: Hemoglobin (g/dl) 14.06±1.88; MCV (fl) 85.70 (55.7-96.5); MCH (pg) 28.45 (17.6-32.5), and ferritin (ng/ml) 31.30 (4-848). There was no difference in terms of blood values between RLS and control group (p>0.05). Sural nerve conduction velocity was slower in patients with RLS (p=0.01). Sural nerve latency was longer (p=0.01). Other nerve conduction parameters were equal in the study and control groups (p>0.05) Conclusion: Central nervous system dopaminergic mechanisms, genetic transmission, and low ferritin levels are the main factors in the pathogenesis of RLS. There is less focus on the peripheral nervous system. In this study, sural nerve conduction velocity and latency were associated with RLS. However, there was no correlation between ferritin levels and nerve conduction.
Journal of the Turkish Epilepsi Society, 2013
Objectives: Restless legs syndrome (RLS) is a common sensory-motor disorder. RLS is characterized by intense restlessness and unpleasant sensation deep inside the legs. The aim of this study was to determine the prevalence of RLS among the epileptic patients who took carbamazepine (CBZ) or valproic acid (VPA) monotherapy and the findings were compared normal subjects and general population. Methods: Patients who took VPA and CBZ monotherapy and followed up at least six months in our department were included in this study. The diagnosis of RLS was made according to the International Restless Legs Syndrome Study Group criteria. Findings were compared with age-sex matched normal subjects and general population. Results: Ninety-two patients were included in this study. Fifty-seven of them were taking VPA and remaining thirty-five were taking CBZ. We found RLS in two (2.2%) of them (one of them taking VPA, the other CBZ). The percentage of RLS in normal subject was 6%. However, this difference was not statistically significant. Conclusion: We interpret this result as indirect evidence of treatment of RLS symptoms with CBZ and VA therapy when the finding was compared with general population and normal subjects.
Restless legs syndrome in end stage chronic renal failure patients receiving hemodialysis treatment
Kafkas Journal of Medical Sciences, 2013
AIM: In this study, we aimed to investigate the frequency of restless legs syndrome and the probable relation between demographic characteristics of the patients diagnosed in patients on hemodialysis treatment program for chronic renal failure in Mardin, Turkey. METHODS: In this study, chronic renal failure patients over 18 years of age, with a Kt/V >1.4 value admitted to the two dialysis centers in Mardin and under hemodialysis program for at least three months were included. For the diagnosis of restless legs syndrome, the diagnosis form of The International Restless Syndrome Legs Study Group was used. The patients were divided into two groups depending on the presence or absence of restless legs syndrome. Demographical and laboratory characteristics of the two groups were compared. RESULTS: The study included all of the 90 patients receiving hemodialysis treatment and restless legs syndrome was diagnosed in eight (8.9%) of these cases. Although the mean duration of hemodialysis treatment was longer in patients with restless legs syndrome, the difference was not signifi cant (p=0.06). The demographic and biochemical characteristics showed no difference between the two groups (p > 0.05). Diabetes Mellitus and hypertension were detected in 44 and 43% of all participants, respectively. CONCLUSION: Restless legs syndrome was detected in 8.9% of chronic renal failure patients receiving hemodialysis treatment. The demographic characteristics of patients in the presence or absence of restless legs syndrome are similar.