Antioxidant effect of Tephrosia purpurea L. roots (original) (raw)

International Journal of Pharmaceutical Sciences and Research, 2010

Abstract

The plant Tephrosia purpurea L. is commonly known as Unhali. T. purpurea (Leguminosae) is a copiously branched perennial herb. Present work was undertaken to study antioxidant potential of the plant. Dried ethanol and aqueous extracts plant were screened for in-vitro antioxidant activity by DPPH assay and nitric oxide screening methods. Results showed that IC50 value of aqueous extract in DPPH assay and nitric oxide scavenging assay are 78 ug/ml and 89 ug/ml respectively. Phytochemical screening revealed that flavonoids, alkaloids, saponins, tannins and phenolic compound are present in aqueous extract and may be responsible for the activity. It can be concluded that the aqueous extract of T. purpurea L. root can be used as antioxidant and it can be recommended for the treatment of various disease.

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