Synthesis of 2-Indol-3-ylbenzofulvenes through a Tandem Reaction Catalyzed by Cationic Gold(I) Complexes (original) (raw)

New Entry to Polycyclic Fused Indoles via Gold(I)‐catalyzed Cascade Reaction

Chemistry – An Asian Journal, 2013

Polycyclic indoles are pivotal motifs in naturally occurring compounds, featuring a plethora of pharmacological and agrochemical applications. [1] Large chemical decoration and nontrivial molecular scaffolds are common architectural patterns in indole-based alkaloids that still trigger organic chemists in developing chemically and economically efficient and sustainable methodologies for their preparation. Accordingly, efforts towards the synthesis of indole derivatives by means of metal as well as metal-free catalysis are growing exponentially. [2] In this realm, N-fused indole alkaloids based on oxazino

Gold(I)-catalyzed tandem cyclization approach to tetracyclic indolines

Organic letters, 2010

Two highly stereoselective cationic gold(I)-catalyzed tandem cyclization reactions of alkynylindoles are described. These reactions demonstrated a novel and general strategy to rapidly construct highly functionalized polycyclic indolines. This approach was successfully employed for a formal synthesis of the akuammiline alkaloid minfiensine.

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