A systematic review of interventions for the treatment for nocturia or nocturnal incontinence in terms of improving symptom severity and quality of life in adult women (original) (raw)
Related papers
What Is the Most Effective Treatment for Nocturia or Nocturnal Incontinence in Adult Women?
European Urology Focus, 2020
Context: Nocturia is a prevalent symptom with varied aetiology and no consensus on treatment options. Objective: We systematically reviewed evidence comparing the benefits and harms of various treatment options for nocturia or nocturnal incontinence in women. Evidence acquisition: Literature search was performed using Embase, Medline, Cochrane databases (from January 1, 1946 to September 26, 2017), following the methods detailed in the Cochrane Handbook. The protocol was registered with PROSPERO. Certainty of evidence was assessed with GRADE approach. Evidence synthesis: The literature search identified 3573 citations, of which 11 full text articles were included. 3 studies on desmopressin and 4 on antimuscarinics provided evidence of improving nocturia symptoms. 4 studies on behavioural treatment provided limited evidence and controversial results. 1 study on oestrogen did not prove the benefit of any mode of administration, and one small study on functional magnetic stimulation provided some evidence of effectiveness in nocturia. One RCT (141 participants) reported a statistically significant difference between the desmopressin and placebo group (desmopressin patients experienced 0.75 (95% CI 0.47-1.03) nocturia episodes less than placebo; certainty of evidence = low). The only RCT on antimuscarinics in women with nocturia reported oxybutynin reduced the number of nocturia episodes by 0.3 (95% CI-0.02 to 0.62) versus placebo. In one RCT comparing tolterodine to the combination of tolterodine with behavioural therapy, there was significant change from baseline nocturnal incontinence episodes in both groups. Conclusions There is some evidence that desmopressin and antimuscarinics are effective treatment options for nocturia, however there is very limited evidence for other treatment options. The findings should be interpreted with caution as there were some methodological flaws in the included studies, particularly outcome heterogeneity. Patient summary This review identified several medical treatments for nocturia in women, such as desmopressin and antimuscarinics, that appear to improve the severity of the condition.
2005
The objective of this study was to estimate the prevalence of nocturia in incontinent women in a urogynaecologic practice and its association with the quality of life and to estimate the prevalences of the pathophysiological categories among nocturics. From 1 January 2002, all patients with complaints of urinary incontinence were analysed according to a specific protocol: multichannel urodynamic testing, a 1-h International Incontinence Society (ICS) pad test and a 3-day frequency-volume (FV) chart. From 1 June 2002, subjects had to fill in a standardised quality of life questionnaire as well. Nocturia was defined as two or more micturitions per night calculated from the FV chart. Evaluable FV charts were received from111 patients, and 72 patients completed the questionnaires correctly. The overall prevalence of nocturia was 48.6% (confidence interval: 43.9-53.3%). Nocturia had a negative impact on several aspects of the quality of life. The maximum voided volume was significantly (p=0.005) less in nocturics. The 24-h frequency was higher in nocturics (p=0.001). Nocturics lost more urine during the pad test (p=0.039). The multivariate logistic regression analysis showed that the greater the proportion of 24-h urine excreted at night, the greater the odds of having nocturia and that the lesser the maximum voided volume, the greater the odds of having nocturia. The majority (92.7%) of the nocturics can be classified into one of the responsible pathophysiologic categories: nocturnal polyuria in 51.2%, a low functional bladder capacity in 14.6%, a combination of both in 9.8%, polyuria in 4.9% and a combination of polyuria and nocturnal polyuria in 12.2% of the cases. Nocturia is a frequent symptom among urinary incontinent patients, with a negative impact on several aspects of the quality of life. With a FV chart, nocturics can be classified into one of the responsible pathophysiologic categories in the majority (92.7%) of the cases.
Assessment of associated factors with nocturia in young and older urinary incontinent
Yeni Üroloji Dergisi
Objective: To assess the factors affecting nocturia in young and older women with urinary incontinence (UI). Material and Methods: Women who applied to the urology outpatient clinic with the UI complaint between November 2021-March 2022 were included. Demographic data, anthropometric measurements, medications and comorbidities were recorded. The ICIQ-SF test was applied to evaluate their quality of life. Patients who have been waking up at night with the need to urinate ≥2 were considered to have nocturia. Results: Ninety-two women were included. Two groups were created as patients <60 years (n=47) and ≥60 years (n=45). The body mass index and waist circumference were higher in patients ≥60 years (respectively; p= 0.034, p= <0.001). Using of diuretic and anticholinergic medications was higher than in the younger group (respectively; p= <0.001, p= 0.006). The total number of medications was higher in the older group (p= <0.001). The number of comorbidities and the number ...